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12/10/2020 10:17:45 AM | Browse: 592 | Download: 1392
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 58403
Country/Territory Taiwan
Received
2020-08-26 03:56
Peer-Review Started
2020-08-26 03:57
To Make the First Decision
Return for Revision
2020-10-21 18:28
Revised
2020-11-10 02:09
Second Decision
2020-11-17 09:59
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-11-17 22:28
Articles in Press
2020-11-17 22:28
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-11-30 23:56
Typeset the Manuscript
2020-12-09 11:33
Publish the Manuscript Online
2020-12-10 10:17
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Observational Study
Article Title Outcomes of neoadjuvant chemoradiotherapy followed by radical resection for T4 colorectal cancer
Manuscript Source Unsolicited Manuscript
All Author List Chun-Ming Huang, Ching-Wen Huang, Cheng-Jen Ma, Hsiang-Lin Tsai, Wei-Chih Su, Tsung-Kun Chang, Ming-Yii Huang and Jaw Yuan Wang
ORCID
Author(s) ORCID Number
Chun-Ming Huang http://orcid.org/0000-0002-2605-9639
Ching-Wen Huang http://orcid.org/0000-0001-8011-8428
Cheng-Jen Ma http://orcid.org/0000-0001-8923-9912
Hsiang-Lin Tsai http://orcid.org/0000-0002-1645-2525
Wei-Chih Su http://orcid.org/0000-0002-9336-0667
Tsung-Kun Chang http://orcid.org/0000-0001-9760-5070
Ming-Yii Huang http://orcid.org/0000-0001-9432-5284
Jaw Yuan Wang http://orcid.org/0000-0002-7705-2621
Funding Agency and Grant Number
Funding Agency Grant Number
Ministry of Science and Technology MOST109-2314-B-037-035
Ministry of Science and Technology MOST109-2314-B-037-046-MY3
Ministry of Science and Technology MOST109-2314-B-037-040
Ministry of Health and Welfare funded by Health and welfare surcharge of tobacco products MOHW109-TDU-B-212-124026
Kaohsiung Medical University Hospital and the Kaohsiung Municipal Ta-Tung Hospital S10903
Kaohsiung Medical University Hospital and the Kaohsiung Municipal Ta-Tung Hospital KMUH108-8R34
Kaohsiung Medical University Hospital and the Kaohsiung Municipal Ta-Tung Hospital KMUH108-8R35
Kaohsiung Medical University Hospital and the Kaohsiung Municipal Ta-Tung Hospital KMUH108-8M33
Kaohsiung Medical University Hospital and the Kaohsiung Municipal Ta-Tung Hospital KMUH108-8M35
Kaohsiung Medical University Hospital and the Kaohsiung Municipal Ta-Tung Hospital KMUH108-8M36
Kaohsiung Medical University Hospital and the Kaohsiung Municipal Ta-Tung Hospital KMUH-DK109003
Kaohsiung Medical University Hospital and the Kaohsiung Municipal Ta-Tung Hospital KMUH-DK109005-3
Corresponding Author Jaw Yuan Wang, MD, PhD, Professor, Department of Surgery and Cancer Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, No. 100, Tz-You 1st Road, Kaohsiung 80708, Taiwan. cy614112@ms14.hinet.net
Key Words T4; Chemoradiotherapy; Pathological complete response; R0 resection; Colorectal cancer; Survival
Core Tip Patients with clinical T4 colorectal cancer have a poor prognosis because of compromised surgical margins. This retrospective study demonstrated that neoadjuvant chemoradiotherapy resulted in high rates of pathological complete response and complete resection for patients with T4 colorectal cancer. An aggressive approach that entails implementing the FOLFOX regimen before, during, and after irradiation is safe and can improve pathological complete response rates. Negative resection margins and pathological complete response are significantly associated with survival. th survival.
Publish Date 2020-12-10 10:17
Citation Huang CM, Huang CW, Ma CJ, Tsai HL, Su WC, Chang TK, Huang MY, Wang JY. Outcomes of neoadjuvant chemoradiotherapy followed by radical resection for T4 colorectal cancer. World J Gastrointest Oncol 2020; 12(12): 1428-1442
URL https://www.wjgnet.com/1948-5204/full/v12/i12/1428.htm
DOI https://dx.doi.org/10.4251/wjgo.v12.i12.1428
Full Article (PDF) WJGO-12-1428.pdf
Full Article (Word) WJGO-12-1428.docx
STROBE Statement 58403-STROBE-Statement-revision.docx
Manuscript File 58403_Auto_Edited_WangTQ.docx
Answering Reviewers 58403-Answering reviewers.pdf
Audio Core Tip 58403-Audio core tip.m4a
Biostatistics Review Certificate 58403-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 58403-Conflict-of-interest statement.pdf
Copyright License Agreement 58403-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 58403-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 58403-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 58403-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 58403-Language certificate.pdf
Peer-review Report 58403-Peer-review(s).pdf
Scientific Misconduct Check 58403-Bing-Yan JP-1.png
Scientific Misconduct Check 58403-Scientific misconduct check.pdf
Scientific Editor Work List 58403-Scientific editor work list.pdf