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Articles Published Processes
11/6/2020 7:36:12 AM | Browse: 756 | Download: 1100
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Received |
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2020-07-22 16:16 |
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Peer-Review Started |
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2020-07-22 16:17 |
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To Make the First Decision |
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Return for Revision |
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2020-08-08 16:43 |
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Revised |
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2020-08-10 08:47 |
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Second Decision |
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2020-09-24 12:51 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-09-25 05:28 |
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Articles in Press |
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2020-09-25 05:28 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-10-10 06:57 |
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Typeset the Manuscript |
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2020-11-05 01:41 |
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Publish the Manuscript Online |
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2020-11-06 07:36 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Origin and genomic characteristics of SARS-CoV-2 and its interaction with angiotensin converting enzyme type 2 receptors, focusing on the gastrointestinal tract
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Michail Galanopoulos, Aris Doukatas and Maria Gazouli |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Michail Galanopoulos, FEBG, MD, PhD, Doctor, Doctor, Department of Gastroenterology, 401 General Military Hospital of Athens, 138 Mesogeion Avenue and Katechaki Street, Athens 11525, Attiki, Greece. galanopoulosdr@gmail.com |
| Key Words |
SARS-CoV-2; COVID-19; Gastrointestinal tract; Angiotensin converting enzyme type 2; Angiotensin converting enzyme type 2 receptor; Renin-angiotensin system |
| Core Tip |
Although the main route of spread and symptomatology of coronavirus disease 2019 is closely related to respiratory tract, the gastrointestinal tract could be an alternative and potential route of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission and manifestation, most probably as a result of the overexpression of angiotensin converting enzyme type 2 (ACE2) receptors in the digestive system. Thus, this review primarily focuses on the analysis of some critical elements about the SARS-CoV-2 genome and its general characteristics, but most importantly intends to highlight the role of ACE2 receptor in both SARS-CoV-2 replication and pathogenesis, especially in the gastrointestinal tract. |
| Publish Date |
2020-11-06 07:36 |
| Citation |
Galanopoulos M, Doukatas A, Gazouli M. Origin and genomic characteristics of SARS-CoV-2 and its interaction with angiotensin converting enzyme type 2 receptors, focusing on the gastrointestinal tract. World J Gastroenterol 2020; 26(41): 6335-6345 |
| URL |
https://www.wjgnet.com/1007-9327/full/v26/i41/6335.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v26.i41.6335 |
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