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8/25/2014 4:06:00 PM | Browse: 928 | Download: 759
Publication Name World Journal of Gastroenterology
Manuscript ID 5856
Country/Territory Italy
Received
2013-09-28 16:28
Peer-Review Started
2013-09-29 14:01
To Make the First Decision
2013-10-22 16:33
Return for Revision
2013-10-23 11:20
Revised
2014-01-11 23:04
Second Decision
2014-04-29 12:20
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-04-29 14:21
Articles in Press
2014-05-23 11:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
2014-05-14 20:24
Typeset the Manuscript
2014-07-14 09:33
Publish the Manuscript Online
2014-07-26 13:36
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Treatment of rectal cancer by transanal endoscopic microsurgery: Experience with 425 patients
Manuscript Source Invited Manuscript
All Author List Mario Guerrieri, Rosaria Gesuita, Roberto Ghiselli, Giovanni Lezoche, Andrea Budassi and Maddalena Baldarelli
Funding Agency and Grant Number
Corresponding Author Mario Guerrieri, MD, Department of General Surgery, Università Politecnica delle Marche, Via Conca 71, 60126 Ancona, Italy. guerrieri.m@libero.it
Key Words Rectal cancer; Transanal endoscopic microsurgery; Chemoradiotherapy; Local excision; Downstaging
Core Tip The gold standard treatment for locally advanced rectal cancer, major surgery, is associated with a high incidence of definitive stoma. In the 1980s, Buess pioneered the removal of rectal lesions with full-thickness excision by transanal endoscopic microsurgery (TEM). It was subsequently demonstrated that T1-N0 lesions can be treated by TEM alone. However, neoadjuvant chemoradiotherapy can downstage T2-T3-N0 lesions and even elicit a complete response. In our experience, the local recurrence and survival rates of selected patients with local-advanced rectal cancer and no nodal involvement treated with neoadjuvant therapy and TEM do not differ significantly from patients treated by major surgery.
Publish Date 2014-07-26 13:36
Citation Guerrieri M, Gesuita R, Ghiselli R, Lezoche G, Budassi A, Baldarelli M. Treatment of rectal cancer by transanal endoscopic microsurgery: Experience with 425 patients. World J Gastroenterol 2014; 20(28): 9556-9563
URL http://www.wjgnet.com/1007-9327/full/v20/i28/9556.htm
DOI http://dx.doi.org/10.3748/wjg.v20.i28.9556
Full Article (PDF) WJG-20-9556.pdf
Full Article (Word) WJG-20-9556.doc
Manuscript File 5856-Review.doc
Answering Reviewers 5856-Answering reviewers.pdf
Copyright License Agreement 5856-Copyright assignment.pdf
Peer-review Report 5856-Peer reviews.pdf
Scientific Editor Work List 5856-Scientific editor work list.pdf