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Articles Published Processes
9/4/2014 3:52:00 PM | Browse: 1282 | Download: 1409
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Received |
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2013-09-28 16:33 |
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Peer-Review Started |
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2013-09-29 14:03 |
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To Make the First Decision |
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2013-10-29 12:32 |
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Return for Revision |
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2013-10-30 10:32 |
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Revised |
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2013-11-05 04:59 |
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Second Decision |
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2013-11-13 12:03 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2013-11-13 15:20 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2014-01-10 14:56 |
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Publish the Manuscript Online |
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2014-01-19 14:17 |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Topic Highlights |
Article Title |
Is irritable bowel syndrome an organic disorder?
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Manuscript Source |
Invited Manuscript |
All Author List |
Magdy El-Salhy, Doris Gundersen, Odd Helge Gilja, Jan Gunnar Hatlebakk and Trygve Hausken |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Helse-Fonna |
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Corresponding Author |
Magdy El-Salhy, Professor, Consultant Gastroenterologist, Section for Gastroenterology, Department of Medicine, Stord Helse-Fonna Hospital, Karmsundgata 120, Box 4000, 5409 Stord, Norway. magdy.el-salhy@helse-fonna.no |
Key Words |
Cholecystokinin; Dysmotility; Endocrine cells; Enteric nervous system; Ghrelin; Peptide YY; Secretion; Secretin; Serotonin; Visceral hypersensitivity |
Core Tip |
This review presents recent observations in irritable bowel syndrome (IBS) patients that point toward the existence of an anatomical defect in the gastrointestinal endocrine cells. It includes also an argument that IBS is an organic disorder and that the abnormalities in the gastrointestinal endocrine cells can explain the visceral hypersensitivity, dysmotility and abnormal secretion reported in these patients. |
Publish Date |
2014-01-19 14:17 |
Citation |
El-Salhy M, Gundersen D, Gilja OH, Hatlebakk JG, Hausken T. Is irritable bowel syndrome an organic disorder? World J Gastroenterol 2014; 20(2): 384-400 |
URL |
http://www.wjgnet.com/1007-9327/full/v20/i2/384.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v20.i2.384 |
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