Publication Name	World Journal of Gastroenterology
Manuscript ID	5857
Country	Norway

Received	2013-09-28 16:33
Peer-Review Started	2013-09-29 14:03
First Decision by Editorial Office Director
Return for Revision	2013-10-30 10:32
Revised	2013-11-05 04:59
Publication Fee Transferred
Second Decision by Editor	2013-11-13 12:03
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2013-11-13 15:20
Articles in Press
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-01-10 14:56
Publish the Manuscript Online	2014-01-19 14:17

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Is irritable bowel syndrome an organic disorder?
Manuscript Source	Invited Manuscript
All Author List	Magdy El-Salhy, Doris Gundersen, Odd Helge Gilja, Jan Gunnar Hatlebakk and Trygve Hausken
Funding Agency and Grant Number	Funding Agency Grant Number Helse-Fonna
Corresponding Author	Magdy El-Salhy, Professor, Consultant Gastroenterologist, Section for Gastroenterology, Department of Medicine, Stord Helse-Fonna Hospital, Karmsundgata 120, Box 4000, 5409 Stord, Norway. magdy.el-salhy@helse-fonna.no
Key Words	Cholecystokinin; Dysmotility; Endocrine cells; Enteric nervous system; Ghrelin; Peptide YY; Secretion; Secretin; Serotonin; Visceral hypersensitivity
Core Tip	This review presents recent observations in irritable bowel syndrome (IBS) patients that point toward the existence of an anatomical defect in the gastrointestinal endocrine cells. It includes also an argument that IBS is an organic disorder and that the abnormalities in the gastrointestinal endocrine cells can explain the visceral hypersensitivity, dysmotility and abnormal secretion reported in these patients.
Publish Date	2014-01-19 14:17
Citation	El-Salhy M, Gundersen D, Gilja OH, Hatlebakk JG, Hausken T. Is irritable bowel syndrome an organic disorder? World J Gastroenterol 2014; 20(2): 384-400
URL	http://www.wjgnet.com/1007-9327/full/v20/i2/384.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i2.384

Full Article (PDF)	WJG-20-384.pdf
Full Article (Word)	WJG-20-384.doc
Manuscript File	5857-Review.doc
Answering Reviewers	5857-Answering reviewers.pdf
Copyright License Agreement	5857-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	5857-Language certificate.pdf
Peer-review Report	5857-Peer reviews.pdf
Scientific Editor Work List	5857-Scientific editor work list.doc