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Articles Published Processes
12/27/2020 5:30:53 AM | Browse: 654 | Download: 1689
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Received |
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2020-07-30 11:01 |
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Peer-Review Started |
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2020-07-30 11:02 |
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To Make the First Decision |
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Return for Revision |
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2020-09-17 17:03 |
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Revised |
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2020-10-01 18:09 |
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Second Decision |
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2020-10-26 14:23 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-10-26 18:09 |
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Articles in Press |
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2020-10-26 18:09 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-11-10 07:24 |
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Typeset the Manuscript |
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2020-12-24 11:33 |
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Publish the Manuscript Online |
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2020-12-27 05:30 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell Biology |
| Manuscript Type |
Basic Study |
| Article Title |
Umbilical cord-derived mesenchymal stem cells preconditioned with isorhamnetin: potential therapy for burn wounds
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Shazmeen Aslam, Irfan Khan, Fatima Jameel, Midhat Batool Zaidi and Asmat Salim |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Asmat Salim, PhD, Professor, Stem Cell Laboratory, Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, University Road, Karachi 74700, Sindh, Pakistan. asmat.salim@iccs.edu |
| Key Words |
Burn wound; Isorhamnetin; Mesenchymal stem cells; Preconditioning; Wound healing; Small molecule |
| Core Tip |
In this study, we propose an improved cell based therapeutic approach by using a cytoprotective chemical compound, isorhamnetin to precondition human umbilical cord mesenchymal stem cells (MSCs) for second degree burn wounds. Findings of the study suggest that transplantation of preconditioned MSCs in rat burn wound model decreases wound progression by downregulation of inflammatory cytokines and restoration of tissue architecture. The study outcome can lead towards an effective cell based treatment strategy for burn wounds to accelerate wound healing and promote skin regeneration. |
| Publish Date |
2020-12-27 05:30 |
| Citation |
Aslam S, Khan I, Jameel F, Zaidi MB, Salim A. Umbilical cord-derived mesenchymal stem cells preconditioned with isorhamnetin: potential therapy for burn wounds. World J Stem Cells 2020; 12(12): 1652-1666 |
| URL |
https://www.wjgnet.com/1948-0210/full/v12/i12/1652.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v12.i12.1652 |
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