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Articles Published Processes
12/13/2020 5:45:32 AM | Browse: 573 | Download: 889
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Received |
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2020-08-03 11:50 |
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Peer-Review Started |
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2020-07-31 13:10 |
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To Make the First Decision |
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Return for Revision |
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2020-09-24 16:42 |
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Revised |
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2020-09-29 07:54 |
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Second Decision |
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2020-10-16 09:32 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-10-19 20:17 |
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Articles in Press |
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2020-10-19 20:17 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-10-27 01:28 |
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Typeset the Manuscript |
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2020-12-02 05:52 |
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Publish the Manuscript Online |
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2020-12-13 05:45 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cardiac & Cardiovascular Systems |
| Manuscript Type |
Minireviews |
| Article Title |
Effects of ketogenic diet and ketone bodies on the cardiovascular system: Concentration matters
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Souad Nasser, Varvara Vialichka, Marta Biesiekierska, Aneta Balcerczyk and Luciano Pirola |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Polish National Science Centre, Project Grant NCN Harmonia |
2019/30/M/NZ3/00682 |
| NAWA/Campusfrance Polonium |
PPN/X/RJ/1876/2019 |
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| Corresponding Author |
Luciano Pirola, PhD, Senior Scientist, Carmen Laboratory, INSERM Unit 1060—Lyon 1 University, CENS ELI-2D Building, 165 Chemin du Grand Revoyet, Pierre Benite 69310, France. luciano.pirola@univ-lyon1.fr |
| Key Words |
Endothelial cells; Ketone bodies; Vascular physiology; β-Hydroxybutyrate; β-Hydroxybutyrylation; Histone post-translational modifications |
| Core Tip |
Ketone bodies, acting as fuel molecules, signaling molecules and epigenetic regulators, improve metabolic health and lifespan. The endothelium and the vascular system are central regulators of the organism’s metabolic state, and become dysfunctional in cardiovascular disease and diabetic complications. While in diabetic ketoacidosis high ketone bodies concentrations are detrimental to the vasculature, ketone bodies in the low-millimolar range may exert beneficial effects on the vascular system. At low concentrations, ketone bodies may prove beneficial to ameliorate vascular function and alleviate cardiovascular disease. |
| Publish Date |
2020-12-13 05:45 |
| Citation |
Nasser S, Vialichka V, Biesiekierska M, Balcerczyk A, Pirola L. Effects of ketogenic diet and ketone bodies on the cardiovascular system: Concentration matters. World J Diabetes 2020; 11(12): 584-595 |
| URL |
https://www.wjgnet.com/1948-9358/full/v11/i12/584.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v11.i12.584 |
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