Publication Name	World Journal of Hepatology
Manuscript ID	58649
Country	Thailand

Received	2020-07-31 15:42
Peer-Review Started	2020-07-31 15:42
To Make the First Decision
Return for Revision	2020-09-21 18:37
Revised	2020-09-29 08:42
Second Decision	2020-10-16 09:08
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2020-10-19 20:16
Articles in Press	2020-10-19 20:16
Publication Fee Transferred
Edit the Manuscript by Language Editor	2020-10-27 01:04
Typeset the Manuscript	2020-12-08 05:31
Publish the Manuscript Online	2020-12-18 05:58

ISSN	1948-5182 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Letter to the Editor
Article Title	Autophagy related protein 9A increase in hepatitis B virus-associated hepatocellular carcinoma and the role in apoptosis
Manuscript Source	Unsolicited Manuscript
All Author List	Ingorn Kimkong and Areerat Kunanopparat
ORCID	Author(s) ORCID Number Ingorn Kimkong http://orcid.org/0000-0002-8731-0356 Areerat Kunanopparat http://orcid.org/0000-0001-6311-7255
Funding Agency and Grant Number
Corresponding Author	Ingorn Kimkong, PhD, Assistant Professor, Department of Microbiology, Faculty of Science, Kasetsart University, Center for Advanced Studies in Tropical Natural Resources, National Research University – Kasetsart University, 50 Thanon Ngamwongwan, Lat Yao, Chatuchak, , Bangkok 10900, Thailand. fsciiok@ku.ac.th
Key Words	Autophagy; Hepatitis B virus; Hepatocellular carcinoma; Autophagy related protein 9A; Apoptosis; HBx
Core Tip	Autophagy related protein 9A (ATG9A) protein expression was increased in tumor liver tissues compared to adjacent non-tumor tissues from hepatocellular carcinoma (HCC) patients with hepatitis B virus infection. We showed that silencing ATG9A increased cell apoptosis of HepG2.2.15 and HepG2 cells. These results suggest that ATG9A protein is involved in the survival of HCC. The inhibition of ATG9A combined with other targets might be a potential drug for HCC treatment.
Publish Date	2020-12-18 05:58
Citation	Kimkong I, Kunanopparat A. Autophagy related protein 9A increase in hepatitis B virus-associated hepatocellular carcinoma and the role in apoptosis. World J Hepatol 2020; 12(12): 1367-1371
URL	https://www.wjgnet.com/1948-5182/full/v12/i12/1367.htm
DOI	https://dx.doi.org/10.4254/wjh.v12.i12.1367

Full Article (PDF)	WJH-12-1367.pdf
Full Article (Word)	WJH-12-1367.docx
Manuscript File	58649-Review-Filipodia.docx
Answering Reviewers	58649-Answering reviewers.pdf
Audio Core Tip	58649-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	58649-Conflict-of-interest statement.pdf
Copyright License Agreement	58649-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	58649-Language certificate.pdf
Peer-review Report	58649-Peer-review(s).pdf
Scientific Misconduct Check	58649-Bing-Yan JP-1.png
Scientific Misconduct Check	58649-Scientific misconduct check.pdf
Scientific Editor Work List	58649-Scientific editor work list.pdf
CrossCheck Report	58649-CrossCheck report.pdf