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Articles Published Processes
11/23/2020 10:54:17 AM | Browse: 820 | Download: 1674
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Received |
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2020-08-02 07:53 |
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Peer-Review Started |
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2020-08-02 07:54 |
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To Make the First Decision |
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Return for Revision |
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2020-09-17 16:50 |
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Revised |
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2020-10-09 03:31 |
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Second Decision |
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2020-10-30 10:36 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-10-30 22:40 |
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Articles in Press |
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2020-10-30 22:40 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-11-17 11:57 |
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Publish the Manuscript Online |
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2020-11-23 10:54 |
| ISSN |
2220-3230 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Donor-specific cell-free DNA as a biomarker in liver transplantation: A review
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Tess McClure, Su Kah Goh, Daniel Cox, Vijayaragavan Muralidharan, Alexander Dobrovic and Adam G Testro |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| The University of Melbourne, Parkville 3000, VIC, Australia |
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| Corresponding Author |
Tess McClure, FRACP, MBBS, Doctor, Doctor, Research Fellow, Department of Liver Transplant Unit, Austin Health, 145 Studley Rd, Heidelberg 3084, VIC, Australia. tess.mcclure@austin.org.au |
| Key Words |
Biomarkers; Precision medicine; Donor-specific cell-free DNA; Liver transplantation; Rejection; Review |
| Core Tip |
Donor-specific cell-free DNA is a biomarker with promising clinical utility in liver transplantation. It demonstrates stereotypic dynamics in states of graft health, and is an early and accurate marker of acute rejection. This has been demonstrated in other solid-organ transplantations, where certain assays have progressed to commercialisation. Further studies examining donor-specific cell free DNA in liver transplantation, such as a randomised controlled trial or in combination with other assays, will assist with its translation into clinical practice. Ultimately, this emerging biomarker will need to be used in an integrated manner by experienced clinicians so as to improve patient outcomes. |
| Publish Date |
2020-11-23 10:54 |
| Citation |
McClure T, Goh SK, Cox D, Muralidharan V, Dobrovic A, Testro AG. Donor-specific cell-free DNA as a biomarker in liver transplantation: A review. World J Transplant 2020; 10(11): 307-319 |
| URL |
https://www.wjgnet.com/2220-3230/full/v10/i11/307.htm |
| DOI |
https://dx.doi.org/10.5500/wjt.v10.i11.307 |
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