Publication Name	World Journal of Gastroenterology
Manuscript ID	5890
Country	Italy

Received	2013-09-28 18:47
Peer-Review Started	2013-09-29 15:34
To Make the First Decision	2013-12-26 10:53
Return for Revision	2014-01-17 09:54
Revised	2013-11-22 17:42
Second Decision	2014-04-03 10:13
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-04-03 12:28
Articles in Press	2014-05-23 11:05
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-04-19 05:26
Typeset the Manuscript	2014-06-08 15:31
Publish the Manuscript Online	2014-06-21 13:56

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Systematic Reviews
Article Title	Association between orofacial granulomatosis and Crohn’s disease in children: Systematic review
Manuscript Source	Invited Manuscript
All Author List	Marzia Lazzerini, Matteo Bramuzzo and Alessandro Ventura
Funding Agency and Grant Number
Corresponding Author	Marzia Lazzerini, PhD, Institute for Maternal and Child Health, IRCCS Burlo Garofolo, Via dell’Istria 65/1, 34137 Trieste, Italy. marzia.lazzerini@burlo.trieste.it
Key Words	Orofacial granulomatosis; Melkersson-Rosenthal syndrome; Cheilitis granulomatosa; Crohn’s disease; Children; Systematic review
Core Tip	This systematic review of children with orofacial granulomatosis (OFG) resulted in the following main findings: (1) 40.4% of children with OFG were affected by Crohn’s disease during their life; (2) 12.1% of children with OFG had perianal disease; (3) 6.4% had a positive family history for Crohn’s disease; (4) both OFG and Crohn’s disease were more prevalent in boys; and (5) both diseases had a long-term course, and treatment resembled the treatment used for Crohn’s disease. Taken together, these findings suggest that OFG may be a subtype of Crohn’s disease.
Publish Date	2014-06-21 13:56
Citation	Lazzerini M, Bramuzzo M, Ventura A. Association between orofacial granulomatosis and Crohn’s disease in children: Systematic review. World J Gastroenterol 2014; 20(23): 7497-7504
URL	http://www.wjgnet.com/1007-9327/full/v20/i23/7497.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i23.7497

Full Article (PDF)	WJG-20-7497.pdf
Full Article (Word)	WJG-20-7497.doc
Manuscript File	5890-Review.doc
Answering Reviewers	5890-Answering reviewers.pdf
Copyright License Agreement	5890-Copyright assignment.pdf
Peer-review Report	5890-Peer reviews.pdf
Scientific Editor Work List	5890-Scientific editor work list.doc