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Articles Published Processes
12/14/2020 8:10:05 AM | Browse: 696 | Download: 1934
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Received |
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2020-09-09 08:33 |
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Peer-Review Started |
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2020-09-09 08:33 |
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To Make the First Decision |
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Return for Revision |
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2020-09-29 23:59 |
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Revised |
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2020-10-09 13:37 |
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Second Decision |
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2020-11-03 09:45 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-11-04 04:34 |
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Articles in Press |
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2020-11-04 04:34 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-11-14 01:48 |
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Typeset the Manuscript |
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2020-12-10 02:18 |
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Publish the Manuscript Online |
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2020-12-14 08:10 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Obstetrics & Gynecology |
| Manuscript Type |
Case Control Study |
| Article Title |
Response of gut microbiota to serum metabolome changes in intrahepatic cholestasis of pregnant patients
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Guo-Hua Li, Shi-Jia Huang, Xiang Li, Xiao-Song Liu and Qiao-Ling Du |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Technology Project of Shanghai Pudong New District Health and Family Planning Commission |
PW2019D-9 |
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| Corresponding Author |
Qiao-Ling Du, PhD, Doctor, Doctor, Department of Obstetrics, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, No.2699, West Gaoke Road, Shanghai 200040, China. qldu2004@126.com |
| Key Words |
Intrahepatic cholestasis in pregnancy; Metabolome; Gut microbiota; Bile acids; ; |
| Core Tip |
This study is the first to investigate the consequences of intrahepatic cholestasis in pregnancy (ICP) with respect to the serum metabolome and gut microbiota. Our data suggest that ICP can cause significant changes in the serum metabolome. Changes in the relative abundance of bile acid-related compounds in serum due to ICP may have an impact on gut microbiota, which in turn may threaten the safety of pregnant women and foetuses. Our findings also suggest a mechanism of ICP that is associated with the microbiota via changes in serum metabolites. |
| Publish Date |
2020-12-14 08:10 |
| Citation |
Li GH, Huang SJ, Li X, Liu XS, Du QL. Response of Gut microbiota to serum metabolome changes in intrahepatic cholestasis of pregnant patients. World J Gastroenterol 2020; 26(46): 7338-7351 |
| URL |
https://www.wjgnet.com/1007-9327/full/v26/i46/7338.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v26.i46.7338 |
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