Publication Name	World Journal of Gastroenterology
Manuscript ID	5915
Country	China

Received	2013-09-28 20:19
Peer-Review Started	2013-09-30 10:33
To Make the First Decision	2013-10-29 12:32
Return for Revision	2013-10-30 10:05
Revised
Second Decision	2013-12-13 14:03
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-12-13 14:59
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2013-12-27 09:45
Typeset the Manuscript	2014-05-05 11:28
Publish the Manuscript Online	2014-05-18 12:31

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Topic Highlights
Article Title	Hepatitis B virus infection and intrahepatic cholangiocarcinoma
Manuscript Source	Invited Manuscript
All Author List	Hua-Bang Zhou, Jing-Yi Hu and He-Ping Hu
Funding Agency and Grant Number
Corresponding Author	He-Ping Hu, MD, Professor, Department I of Hepatobiliary Diseases, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, No. 225 Changhai Road, Shanghai 200438, China. hp-hu@medmail.com.cn
Key Words	Hepatitis B virus; Intrahepatic cholangiocarcinoma; Epidemiology; Etiopathogenesis
Core Tip	Intrahepatic cholangiocarcinoma (ICC) is a devastating malignant tumor. Its incidence and mortality is increasing drastically over the past two decades worldwide, though the cause for this rise in incidence is unclear. The etiology and carcinogenesis of ICC remain inconclusive. Recent studies suggest that hepatitis B virus (HBV) infection plays an important etiological role in ICC development. HBV-associated ICC holds many clinicopathological similarities with HBV-associated hepatocellular carcinoma (HCC), and HBV-associated ICC patients may have a better prognosis than ICC patients without HBV infection. HBV-associated ICC and HBV-associated HCC may share a common disease process for carcinogenesis, through a similar long-term inflammatory carcinogenic process, and both possibly arise from hepatic progenitor cells.
Publish Date	2014-05-18 12:31
Citation	Zhou HB, Hu JY, Hu HP. Hepatitis B virus infection and intrahepatic cholangiocarcinoma. World J Gastroenterol 2014; 20(19): 5721-5729
URL	http://www.wjgnet.com/1007-9327/full/v20/i19/5721.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i19.5721

Full Article (PDF)	WJG-20-5721.pdf
Full Article (Word)	WJG-20-5721.doc
Manuscript File	5915-Review.doc
Answering Reviewers	5915-Answering reviewers.pdf
Copyright License Agreement	5915-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	5915-Language certificate.pdf
Peer-review Report	5915-Peer reviews.pdf
Scientific Editor Work List	5915-Scientific editor work list.doc