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Articles Published Processes
12/4/2020 6:04:55 AM | Browse: 504 | Download: 1482
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Received |
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2020-09-17 14:36 |
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Peer-Review Started |
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2020-09-17 14:36 |
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To Make the First Decision |
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Return for Revision |
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2020-10-17 23:06 |
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Revised |
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2020-10-30 02:44 |
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Second Decision |
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2020-11-06 10:15 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-11-09 00:56 |
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Articles in Press |
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2020-11-09 00:56 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-11-13 02:40 |
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Typeset the Manuscript |
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2020-12-02 13:05 |
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Publish the Manuscript Online |
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2020-12-04 06:04 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Transplantation |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
High mortality associated with gram-negative bacterial bloodstream infection in liver transplant recipients undergoing immunosuppression reduction
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Fang Chen, Xiao-Yun Pang, Chuan Shen, Long-Zhi Han, Yu-Xiao Deng, Xiao-Song Chen, Jian-Jun Zhang, Qiang Xia and Yong-Bing Qian |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Key R&D Precision Medicine Program |
2017YFC0908100 |
| Shanghai Key Clinical Specialty Grant |
Shslczdzk05801 |
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| Corresponding Author |
Yong-Bing Qian, MD, Associate Professor, Department of Liver Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, No. 1630, Dongfang Road, Shanghai 200127, China. qianyb79@hotmail.com |
| Key Words |
Immunosuppressive therapy; Liver transplantation; Bloodstream infection; Multidrug-resistant gram-negative bacterium; ; |
| Core Tip |
Bacterial infections are the most common infectious complication after liver transplantation (LT). Immunosuppression (IS) reduction is usually needed in case of bacterial infections in LT recipients. However, we do not know exactly the incidence of IS reduction during bloodstream infection after LT and its effect on patient outcome. This single-center analysis summarized the IS reduction data in 70 LT recipients. We found IS reduction is more frequently associated with gram-negative bacterial infection than gram-positive bacterial infection in LT recipients. Complete withdrawal of immunosuppression should be cautious due to increased risk of mortality. |
| Publish Date |
2020-12-04 06:04 |
| Citation |
Chen F, Pang XY, Shen C, Han LZ, Deng YX, Chen XS, Zhang JJ, Xia Q, Qian YB. High mortality associated with Gram-negative bacterial bloodstream infection in liver transplant recipients undergoing immunosuppression reduction. World J Gastroenterol 2020; 26(45): 7191-7203 |
| URL |
https://www.wjgnet.com/1007-9327/full/v26/i45/7191.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v26.i45.7191 |
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