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Articles Published Processes
9/3/2014 2:27:00 PM | Browse: 1614 | Download: 2298
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Received |
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2013-09-28 21:51 |
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Peer-Review Started |
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2013-09-30 12:08 |
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To Make the First Decision |
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2013-11-04 19:39 |
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Return for Revision |
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2013-11-05 09:22 |
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Revised |
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2013-11-19 23:19 |
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Second Decision |
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2014-01-06 18:34 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-01-06 18:48 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2014-01-21 17:37 |
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Publish the Manuscript Online |
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2014-02-20 19:40 |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Topic Highlights |
Article Title |
Role of the gut microbiota in inflammatory bowel disease pathogenesis: What have we learnt in the past 10 years?
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Manuscript Source |
Invited Manuscript |
All Author List |
Georgina L Hold, Megan Smith, Charlie Grange, Euan Robert Watt, Emad M El-Omar and Indrani Mukhopadhya |
Funding Agency and Grant Number |
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Corresponding Author |
Indrani Mukhopadhya, PhD, Gastrointestinal Research Group, Division of Applied Medicine, University of Aberdeen, Foresterhill, Aberdeen AB252ZD, United Kingdom. indrani.mukhopadhya@abdn.ac.uk |
Key Words |
Inflammatory bowel disease; Crohn’s disease; Ulcerative colitis; Gut microbiota; Innate immune response; Probiotics; Prebiotics; Faecal transplant |
Core Tip |
In the last decade there have been enormous strides in our understanding of the role of gut microbiota in the aetiopathogenesis of inflammatory bowel disease (IBD). Newer molecular and genetic diagnostic tools have elucidated distinct changes in the gut microbiota in IBD patients and clarified the deficiencies of innate immunity. A link between environmental factors like diet, host immunity and the gut microbiota has been established. This review aims to enumerate these diverse strands of converging research in the last decade to outline the exciting prospects of possible personalized therapeutic interventions for patients with IBD in the coming years. |
Publish Date |
2014-02-20 19:40 |
Citation |
Hold GL, Smith M, Grange C, Watt ER, El-Omar EM, Mukhopadhya I. Role of the gut microbiota in inflammatory bowel disease pathogenesis: What have we learnt in the past 10 years? World J Gastroenterol 2014; 20(5): 1192-1210 |
URL |
http://www.wjgnet.com/1007-9327/full/v20/i5/1192.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v20.i5.1192 |
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