Publication Name	World Journal of Gastroenterology
Manuscript ID	5971
Country	Japan

Received	2013-09-29 09:22
Peer-Review Started	2013-09-30 14:10
To Make the First Decision	2013-10-22 16:48
Return for Revision	2013-10-23 10:08
Revised	2013-11-13 21:19
Second Decision	2013-11-29 11:24
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-11-30 01:28
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-12-17 13:48
Publish the Manuscript Online	2014-01-20 16:41

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Cellular reprogramming and hepatocellular carcinoma development
Manuscript Source	Invited Manuscript
All Author List	Yun-Wen Zheng, Yun-Zhong Nie and Hideki Taniguchi
Funding Agency and Grant Number	Funding Agency Grant Number Ministry of Education, Culture, Sports, Science and Technology of Japan 18591421 Ministry of Education, Culture, Sports, Science and Technology of Japan 20591531 Ministry of Education, Culture, Sports, Science and Technology of Japan 23591872 Research Center Network for Realization of Regenerative Medicine Japan Science and Technology Agency 62890004
Corresponding Author	Hideki Taniguchi, MD, PhD, Department of Regenerative Medicine, Graduate School of Medicine, Yokohama City University, 3-9 Fuku-ura, Kanazawa-ku, Yokohama, Kanagawa 236-0004, Japan. rtanigu@med.yokohama-cu.ac.jp
Key Words	Reprogramming; Hepatocellular carcinomas; Cancer stem cells; Transcription factor; Therapeutics
Core Tip	Cellular reprogramming contributes to chemoresistance and radioresistance and cancer recurrence in hepatocellular carcinoma (HCC). Recent findings on cellular reprogramming in HCC are summarized and discussed, including stemness transcription factors, DNA methylation, miRNAs, tumor microenvironments, and signaling pathways. The novel therapeutic concept of reprogramming control therapy is also described, which may be a promising strategy for HCC therapy in the future.
Publish Date	2014-01-20 16:41
Citation	Zheng YW, Nie YZ, Taniguchi H. Cellular reprogramming and hepatocellular carcinoma development. World J Gastroenterol 2013; 19(47): 8850-8860
URL	http://www.wjgnet.com/1007-9327/full/v19/i47/8850.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i47.8850

Full Article (PDF)	WJG-19-8850.pdf
Manuscript File	5971-Review.doc
Answering Reviewers	5971-Answering reviewers.pdf
Copyright License Agreement	5971-Copyright assignment.pdf
Peer-review Report	5971-Peer review(s).pdf
Scientific Editor Work List	5971-Scientific editor work list.doc