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Articles Published Processes
12/14/2020 8:10:05 AM | Browse: 707 | Download: 1672
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Received |
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2020-09-27 15:10 |
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Peer-Review Started |
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2020-09-27 15:10 |
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To Make the First Decision |
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Return for Revision |
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2020-10-17 19:00 |
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Revised |
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2020-10-28 01:08 |
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Second Decision |
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2020-11-02 12:27 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-11-04 04:33 |
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Articles in Press |
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2020-11-04 04:33 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-11-14 01:47 |
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Typeset the Manuscript |
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2020-12-03 09:25 |
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Publish the Manuscript Online |
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2020-12-14 08:10 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Control Study |
| Article Title |
Colonic vitamin D receptor expression is inversely associated with disease activity and jumonji domain-containing 3 in active ulcerative colitis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hong-Qian Wang, Wen-Hui Zhang, Ya-Qi Wang, Xiao-Pan Geng, Ming-Wei Wang, Yuan-Yuan Fan, Jing Guan, Ji-Long Shen and Xi Chen |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| The Key Projects of Natural Science Research of Anhui Province in China |
201904a07020043 |
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| Corresponding Author |
Xi Chen, PhD, Professor, Department of Gastroenterology, The First Affiliated Hospital of Anhui Medical University, No. 218 Jixi Road, Hefei 230022, Anhui Province, China. ayfychenxi@163.com |
| Key Words |
Vitamin D; Ulcerative colitis; Disease activity; Vitamin D receptor; Jumonji domain-containing 3; Trimethylated H3 lysine 27 |
| Core Tip |
This is the first report of the relationship between serum vitamin D, vitamin D receptor (VDR), Jumonji domain-containing 3 (Jmjd3) and trimethylated H3 lysine 27 expression and pathological activity in patients with active ulcerative colitis (UC). In active UC, vitamin D level was negatively correlated with disease activity and positively correlated with VDR expression. Furthermore, colonic Jmjd3 expression significantly increased, while trimethylated H3 lysine 27 decreased in UC patients. These findings indicate that VDR expression was inversely related to Jmjd3 expression and disease activity in the colonic mucosa of patients with UC. |
| Publish Date |
2020-12-14 08:10 |
| Citation |
Wang HQ, Zhang WH, Wang YQ, Geng XP, Wang MW, Fan YY, Guan J, Shen JL, Chen X. Colonic vitamin D receptor expression is inversely associated with disease activity and jumonji domain-containing 3 in active ulcerative colitis. World J Gastroenterol 2020; 26(46): 7352-7366 |
| URL |
https://www.wjgnet.com/1007-9327/full/v26/i46/7352.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v26.i46.7352 |
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