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Articles Published Processes
1/20/2021 12:47:16 PM | Browse: 304 | Download: 526
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Received |
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2020-10-03 15:40 |
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Peer-Review Started |
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2020-10-03 15:40 |
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To Make the First Decision |
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Return for Revision |
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2020-11-23 07:26 |
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Revised |
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2020-12-02 20:02 |
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Second Decision |
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2020-12-14 08:16 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2020-12-16 20:20 |
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Articles in Press |
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2020-12-16 20:20 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2021-01-13 11:16 |
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Publish the Manuscript Online |
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2021-01-20 12:47 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Role of ammonia in predicting the outcome of patients with acute-on-chronic liver failure
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Stefan Chiriac, Carol Stanciu, Camelia Cojocariu, Ana-Maria Singeap, Catalin Sfarti, Tudor Cuciureanu, Irina Girleanu, Razvan Alexandru Igna and Anca Trifan |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Camelia Cojocariu, MD, PhD, Assistant Professor, Doctor, Department of Gastroenterology, “Grigore T. Popa” University of Medicine and Pharmacy, 16 Universitatii Street, Iasi 700115, Iasi, Romania. cameliacojocariu@yahoo.com |
| Key Words |
Venous ammonia; Hepatic encephalopathy; Acute-on-chronic liver failure; Asian Pacific Association for the Study of the Liver Acute-on-chronic Liver Failure Research Consortium score; Cirrhosis; Mortality |
| Core Tip |
Hyperammonemia has been associated with hepatic encephalopathy and high mortality in patients with liver cirrhosis. Acute-on-chronic liver failure is a relatively new defined syndrome presenting high 28-d mortality. The role of hyperammonemia in acute-on-chronic liver failure has not yet been clearly established. Venous ammonia presents a good predictive value for in-hospital mortality in patients with acute-on-chronic liver failure (ACLF), with a cut-off value of 152.5 μmol/L, sensitivity = 0.706, 1-specificity = 0.190 and is associated with severe hepatic encephalopathy in patients with ACLF. Thus, venous ammonia has the potential to be used as a prognostic marker in the evaluation of patients with ACLF. |
| Publish Date |
2021-01-20 12:47 |
| Citation |
Chiriac S, Stanciu C, Cojocariu C, Singeap AM, Sfarti C, Cuciureanu T, Girleanu I, Igna RA, Trifan A. Role of ammonia in predicting the outcome of patients with acute-on-chronic liver failure. World J Clin Cases 2021; 9(3): 552-564 |
| URL |
https://www.wjgnet.com/2307-8960/full/v9/i3/552.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v9.i3.552 |
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