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Articles Published Processes
8/14/2021 11:08:14 AM | Browse: 506 | Download: 1135
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Received |
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2021-02-24 17:54 |
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Peer-Review Started |
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2021-02-24 18:04 |
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To Make the First Decision |
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Return for Revision |
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2021-04-19 04:50 |
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Revised |
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2021-05-03 15:41 |
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Second Decision |
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2021-07-09 03:28 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-07-09 12:04 |
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Articles in Press |
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2021-07-09 12:04 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2021-08-09 02:01 |
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Publish the Manuscript Online |
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2021-08-14 11:08 |
ISSN |
1948-5204 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Oncology |
Manuscript Type |
Retrospective Cohort Study |
Article Title |
Neutrophil-to-lymphocyte ratio and carbohydrate antigen 19-9 as prognostic markers for advanced pancreatic cancer patients receiving first-line chemotherapy
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Kabsoo Shin, Eun-Kyo Jung, Se Jun Park, Sangwoon Jeong, In-Ho Kim and Myung-ah Lee |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Myung-ah Lee, MD, PhD, Professor, Division of Medical Oncology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Secho-gu, Seoul 06591, South Korea. angelamd@catholic.ac.kr |
Key Words |
Pancreatic adenocarcinoma; Serum carbohydrate antigen 19-9; Neutrophil-to-lymphocyte ratio; Multivariate analysis; Prognosis; Chemotherapy |
Core Tip |
In pancreatic cancer patients treated with first-line chemotherapy, carbohydrate antigen 19-9 (CA19-9) decline is considered as a prognostic marker. However, there has been no consensus regarding the degree of CA19-9 decline, and certain populations show false negativity. We evaluated the cut-off value of decline of CA19-9 and post-treatment neutrophil-to-lymphocyte ratio (NLR) as prognostic makers. Combination of post-treatment NLR (< 2.62) and decline of CA19-9 (≥ 18%) for CA19-9 positive group or post-treatment NLR alone for CA19-9 negative group could be used as a prognostic marker and an adjuvant tool for response evaluation. |
Publish Date |
2021-08-14 11:08 |
Citation |
Shin K, Jung EK, Park SJ, Jeong S, Kim IH, Lee MA. Neutrophil-to-lymphocyte ratio and carbohydrate antigen 19-9 as prognostic markers for advanced pancreatic cancer patients receiving first-line chemotherapy. World J Gastrointest Oncol 2021; 13(8): 915-928 |
URL |
https://www.wjgnet.com/1948-5204/full/v13/i8/915.htm |
DOI |
https://dx.doi.org/10.4251/wjgo.v13.i8.915 |
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