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Articles Published Processes
3/25/2021 6:36:58 AM | Browse: 478 | Download: 957
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Received |
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2020-10-06 12:52 |
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Peer-Review Started |
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2020-10-06 12:53 |
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To Make the First Decision |
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Return for Revision |
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2020-12-24 20:43 |
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Revised |
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2021-01-08 09:50 |
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Second Decision |
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2021-01-21 03:52 |
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Accepted by Journal Editor-in-Chief |
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2021-01-22 01:58 |
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Accepted by Executive Editor-in-Chief |
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2021-02-15 18:19 |
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Articles in Press |
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2021-02-15 18:19 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-02-26 00:41 |
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Typeset the Manuscript |
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2021-03-24 06:12 |
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Publish the Manuscript Online |
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2021-03-25 06:36 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Mesenchymal stromal cell-dependent immunoregulation in chemically induced acute liver failure
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jia-Hang Zhou, Xuan Lu, Cui-Lin Yan, Xin-Yu Sheng and Hong-Cui Cao |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81971756 |
| Stem Cell and Translational Research from National Key Research and Development Program of China |
2016YFA0101001 |
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| Corresponding Author |
Hong-Cui Cao, MD, PhD, Professor, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, No. 79 Qingchun Road, Hangzhou 310003, Zhejiang Province, China. hccao@zju.edu.cn |
| Key Words |
Mesenchymal stromal cell; Immune response; Drug-induced liver injury; Acute liver failure; Dendritic cell |
| Core Tip |
Drug-induced liver injury (DILI) is a crucial cause of acute liver failure (ALF). Although mesenchymal stromal cells (MSCs) have not been applied to DILI in clinical trials, their efficacy has been proven in various animal models of chemically induced ALF. Immune system disorders play key roles in chemically induced ALF, and MSCs are able to regulate the immune system through soluble factors and cell-to-cell contact, and eventually improve liver damage. We herein discuss the immunomodulatory properties of MSCs in different animal models that mimic the pathology of DILI in humans. |
| Publish Date |
2021-03-25 06:36 |
| Citation |
Zhou JH, Lu X, Yan CL, Sheng XY, Cao HC. Mesenchymal stromal cell-dependent immunoregulation in chemically induced acute liver failure. World J Stem Cells 2021; 13(3): 208-220 |
| URL |
https://www.wjgnet.com/1948-0210/full/v13/i3/208.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v13.i3.208 |
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