9/18/2014 7:49:00 PM | Browse: 1317 | Download: 1232
Publication Name | World Journal of Gastroenterology |
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Manuscript ID | 5995 |
Country | Germany |
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ISSN | 1007-9327 (print) and 2219-2840 (online) |
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Open Access | |
Copyright | |
Article Reprints | For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247 |
Permissions | For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207 |
Publisher | Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website | http://www.wjgnet.com |
Category | Immunology |
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Manuscript Type | Topic Highlights |
Article Title | Helicobacter pylori vaccination: Is there a path to protection? |
Manuscript Source | Invited Manuscript |
All Author List | Florian Anderl and Markus Gerhard |
Funding Agency and Grant Number | |
Corresponding Author | Markus Gerhard, MD, Institute for Medical Microbiology, Immunology and Hygiene, Technische Universität München, Trogerstrasse 30, Munich 81675, Germany. markus.gerhard@tum.de |
Key Words | Helicobacter pylori; Vaccination; Immune response; Dendritic cells; T-cells |
Core Tip | Helicobacter pylori (H. pylori) is a carcinogenic pathogen colonizing the human stomach. In the advent of rising antibiotic resistance, it is of major interest to introduce novel therapies. Immunization is a potent candidate although all efforts to generate an effective vaccine have failed as yet. The host-pathogen interaction and especially the immune-modulating capacity of H. pylori contribute to this development of resistance to treatment. In this review potential solutions with a focus on the immune response to the pathogen are discussed. |
Publish Date | 2014-09-18 19:50 |
Citation | Anderl F, Gerhard M. Helicobacter pylori vaccination: Is there a path to protection? World J Gastroenterol 2014; 20(34): 11939-11949 |
URL | http://www.wjgnet.com/1007-9327/full/v20/i34/11939.htm |
DOI | http://dx.doi.org/10.3748/wjg.v20.i34.11939 |
Full Article (PDF) | WJG-20-11939.pdf |
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Full Article (Word) | WJG-20-11939.doc |
Manuscript File | 5995-Review.docx |
Answering Reviewers | 5995-Answering reviewers.pdf |
Copyright License Agreement | 5995-Copyright assignment.pdf |
Peer-review Report | 5995-Peer review(s).pdf |
Scientific Editor Work List | 5995-Scientific editor work list.pdf |