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Articles Published Processes
1/29/2021 7:57:41 AM | Browse: 786 | Download: 1850
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Received |
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2020-10-12 16:26 |
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Peer-Review Started |
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2020-10-12 16:29 |
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To Make the First Decision |
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Return for Revision |
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2020-11-23 06:07 |
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Revised |
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2020-11-30 14:24 |
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Second Decision |
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2020-12-16 10:44 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-12-16 23:50 |
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Articles in Press |
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2020-12-16 23:50 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-01-15 11:47 |
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Typeset the Manuscript |
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2021-01-28 01:04 |
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Publish the Manuscript Online |
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2021-01-29 07:57 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Microbiology |
Manuscript Type |
Basic Study |
Article Title |
Changes in gut microbiota composition and diversity associated with post-cholecystectomy diarrhea
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Yan-Dong Li, Bao-Ning Liu, Si-Hai Zhao, Yong-Li Zhou, Liang Bai and En-Qi Liu |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
En-Qi Liu, PhD, Director, Director, Professor, Laboratory Animal Center, Institute of Atherosclerotic Disease, Xi’an Jiaotong University, No. 76 Yanta West Road, Xi’an 710061, Shaanxi Province, China. liuenqi@mail.xjtu.edu.cn |
Key Words |
Cholecystectomy; Post-cholecystectomy; Diarrhea; 16S rRNA; Microbiota; Bifidobacterium |
Core Tip |
Post-cholecystectomy diarrhea (PCD) is a difficult problem to treat. About 12%–35.6% of post-cholecystectomy patients have varying degrees of chronic diarrhea. Little is known regarding the intestinal microbiota characteristics in PCD patients. we used high-throughput sequencing of the 16S rRNA gene to characterize the composition and diversity of the complex intestinal microbial community for the PCD patients. The results indicates that decreased diversity and abundance of the microbial community in the PCD group may cause diarrhea. Study findings demonstrate the association between PCD and the gut microbiota, especially regarding Prevotella and Bifidobacterium. Thus, this study provides new insights into potential therapeutics that could target the microbiota to attenuate PCD. |
Publish Date |
2021-01-29 07:57 |
Citation |
Li YD, Liu BN, Zhao SH, Zhou YL, Bai L, Liu EQ. Changes in gut microbiota composition and diversity associated with post-cholecystectomy diarrhea. World J Gastroenterol 2021; 27(5): 391-403 |
URL |
https://www.wjgnet.com/1007-9327/full/v27/i5/391.htm |
DOI |
https://dx.doi.org/10.3748/wjg.v27.i5.391 |
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