Publication Name	World Journal of Stem Cells
Manuscript ID	60089
Country	Brazil

Received	2020-10-14 16:19
Peer-Review Started	2020-10-14 16:19
To Make the First Decision
Return for Revision	2020-12-12 21:06
Revised	2020-12-26 02:13
Second Decision	2021-02-18 03:47
Accepted by Journal Editor-in-Chief	2021-02-19 00:59
Accepted by Executive Editor-in-Chief	2021-02-25 18:15
Articles in Press	2021-02-25 18:15
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-03-25 07:52
Typeset the Manuscript	2021-04-15 13:40
Publish the Manuscript Online	2021-04-22 10:31

ISSN	1948-0210 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Orthopedics
Manuscript Type	Minireviews
Article Title	Orthobiologics in the treatment of hip disorders
Manuscript Source	Unsolicited Manuscript
All Author List	André Vinícius Saueressig Kruel, Lucas Leite Ribeiro, Paulo David Gusmão, Stephany Cares Huber and José Fábio Santos Duarte Lana
ORCID	Author(s) ORCID Number André Vinícius Saueressig Kruel http://orcid.org/0000-0002-7415-3953 Lucas Leite Ribeiro http://orcid.org/0000-0001-5944-2215 Paulo David Gusmão http://orcid.org/0000-0002-3340-1092 Stephany Cares Huber http://orcid.org/0000-0003-3322-0598 José Fábio Santos Duarte Lana http://orcid.org/0000-0002-2330-3982
Funding Agency and Grant Number
Corresponding Author	André Vinícius Saueressig Kruel, MD, Chief Doctor, Surgeon, Department of Orthopedics, Regenesis Clínica Médica, No. 333 Doutor José Mário Mônaco Street, Bento Gonçalves 95700-066, RS, Brazil. kruel.andre@gmail.com
Key Words	Orthobiologics; Hip disorders; Platelet-rich plasma; Mesenchymal stem cells; Bone marrow; Adipose tissue
Core Tip	Orthobiologics are biological materials that are intended for the regeneration or healing of bone, cartilage and soft tissues. Commonly discussed orthobiologics include hyaluronic acid, platelet-rich plasma, bone marrow, adipose tissue and expanded mesenchymal stem cells. We explain the concepts and definitions of each orthobiologic and the literature regarding the use for the hip joint. Each biological therapy has its own benefits and indications; however, it is important to note that the characterization of orthobiologics, injection method and evaluation analysis are of major importance for the use of biological therapies.
Publish Date	2021-04-22 10:31
Citation	Orthobiologics are biological materials that are intended for the regeneration or healing of bone, cartilage and soft tissues. Commonly discussed orthobiologics include hyaluronic acid, platelet-rich plasma, bone marrow, adipose tissue and expanded mesenchymal stem cells. We explain the concepts and definitions of each orthobiologic and the literature regarding the use for the hip joint. Each biological therapy has its own benefits and indications; however, it is important to note that the characterization of orthobiologics, injection method and evaluation analysis are of major importance for the use of biological therapies. World J Stem Cells 2021; 13(4): 304-316
URL	https://www.wjgnet.com/1948-0210/full/v13/i4/304.htm
DOI	https://dx.doi.org/10.4252/wjsc.v13.i4.304

Full Article (PDF)	WJSC-13-304.pdf
Full Article (Word)	WJSC-13-304.docx
Manuscript File	60089_Auto_Edited_LM-Webster J-Clear.docx
Answering Reviewers	60089-Answering reviewers.pdf
Audio Core Tip	60089-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	60089-Conflict-of-interest statement.pdf
Copyright License Agreement	60089-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	60089-Language certificate.pdf
Peer-review Report	60089-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	60089-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	60089-Bing-Yan JP-1.png
Scientific Misconduct Check	60089-Scientific misconduct check.pdf
Scientific Editor Work List	60089-Scientific editor work list.pdf
CrossCheck Report	60089-CrossCheck Report.pdf