Publication Name	World Journal of Gastroenterology
Manuscript ID	6024
Country	Canada

Received	2013-09-29 19:27
Peer-Review Started	2013-09-30 17:35
To Make the First Decision	2013-10-29 12:34
Return for Revision	2013-10-30 13:24
Revised	2013-11-14 22:00
Second Decision	2013-12-05 19:26
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-12-06 12:05
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-12-26 15:48
Publish the Manuscript Online	2014-01-20 17:10

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Hepatocyte nuclear factor 4-alpha involvement in liver and intestinal inflammatory networks
Manuscript Source	Invited Manuscript
All Author List	Jean-Philippe Babeu and François Boudreau
Funding Agency and Grant Number
Corresponding Author	François Boudreau, PhD, Département d’Anatomie et de Biologie Cellulaire, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke J1E 4K8, Québec, Canada. francois.boudreau@usherbrooke.ca
Key Words	Hepatocyte nuclear factor 4-alpha; Inflammatory bowel diseases; Colitis-associated cancer; Gastrointestinal tract; Intestinal epithelium barrier; Inflammation
Core Tip	Hepatocyte nuclear factor 4-alpha (HNF4-α) is an important regulator of liver and intestinal epithelial cells function. Over the last years, HNF4-α has been associated with inflammatory bowel diseases following results obtained from knockout mice and human genome-wide association studies. However, no review has been published on the subject yet and no link with its known role in liver inflammation has been discussed. This review will gather for the first time all the current knowledge about the role of HNF4-α in gut inflammation, the potential impact of its isoforms in its role and hypotheses about the possible biological mechanisms involved.
Publish Date	2014-01-20 17:10
Citation	Babeu JP, Boudreau F. Hepatocyte nuclear factor 4-alpha involvement in liver and intestinal inflammatory networks. World J Gastroenterol 2014; 20(1): 22-30
URL	http://www.wjgnet.com/1007-9327/full/v20/i1/22.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i1.22

Manuscript File	6024-Review.docx
Answering Reviewers	6024-Answering reviewers.pdf
Copyright License Agreement	6024-Copyright assignment.pdf
Peer-review Report	6024-Peer review.pdf
Scientific Editor Work List	6024-Scientific editor work list.doc