Publication Name	World Journal of Stem Cells
Manuscript ID	6025
Country	United States

Received	2013-09-29 19:33
Peer-Review Started	2013-09-30 17:40
To Make the First Decision	2013-10-21 11:04
Return for Revision	2013-10-21 15:27
Revised	2013-11-10 03:54
Second Decision	2013-12-10 16:31
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-12-11 09:50
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-01-26 17:05
Publish the Manuscript Online	2014-02-15 15:06

ISSN	1948-0210 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Hematology
Manuscript Type	Topic Highlights
Article Title	Dendritic cells derived from pluripotent stem cells: potential of large scale production
Manuscript Source	Invited Manuscript
All Author List	Yan Li, Meimei Liu and Shang-Tian Yang
Funding Agency and Grant Number	Funding Agency Grant Number Florida State University start up fund(In part) Florida State University Research Foundation GAP award(In part) National Science Foundation 1342192(In part)
Corresponding Author	Shang-Tian Yang, Professor, William G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, 140 West 19th Ave, Columbus, OH 43210, United States. yang.15@osu.edu
Key Words	Pluripotent stem cells; dendritic cells; bioreactor; hematopoietic differentiation; large scale production
Core Tip	Human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs) are promising sources for hematopoietic cells. This review summarizes recent advances in differentiating hESCs and hiPSCs to dendritic cells (DCs), which are unique immune cells in the hematopoietic system and can be loaded with tumor specific antigen and used as vaccine for cancer immunotherapy. While autologous DCs from peripheral blood are limited in number, human PSC (hPSC)-derived DCs provide a novel alternative cell source for clinical application. Different strategies and effects of shear stress on large-scale production of hPSC-derived DCs in bioreactors are also discussed.
Publish Date	2014-02-15 15:06
Citation	Li Y, Liu M, Yang ST. Dendritic cells derived from pluripotent stem cells: Potential of large scale production. World J Stem Cells 2014; 6(1): 1-10
URL	http://www.wjgnet.com/1948-0210/full/v6/i1/1.htm
DOI	http://dx.doi.org/10.4252/ wjsc.v6.i1.1

Manuscript File	6025-Review.docx
Answering Reviewers	6025-Answering reviewers.pdf
Copyright License Agreement	6025-Copyright assignment.pdf
Peer-review Report	6025-Peer review(s).pdf
Scientific Editor Work List	6025-Scientific editor work list.doc