Publication Name	World Journal of Gastroenterology
Manuscript ID	6029
Country	Taiwan

Received	2013-09-30 08:02
Peer-Review Started	2013-09-30 17:59
First Decision by Editorial Office Director
Return for Revision	2013-10-30 13:26
Revised
Publication Fee Transferred
Second Decision by Editor	2013-12-05 19:26
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2013-12-06 12:06
Articles in Press
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-12-11 11:10
Publish the Manuscript Online	2014-01-20 16:41

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Target genes discovery through copy number alteration analysis in human hepatocellular carcinoma
Manuscript Source	Invited Manuscript
All Author List	De-Leung Gu, Yen-Hsieh Chen, Jou-Ho Shih, Chi-Hung Lin, Yuh-Shan Jou and Chian-Feng Chen
Funding Agency and Grant Number	Funding Agency Grant Number National Research Program for Biopharmaceuticals 101-2320-B-010-066-MY3 National Science Council, Taiwan 101-2325-B-001-011 National Science Council, Taiwan 101-2320-B-001 -029-MY3
Corresponding Author	Chian-Feng Chen PhD, VYM Genome Research Center, National Yang-Ming University, 155 Linong Street, Sec.2, Taipei 11221, Taiwan. cfchen@ym.edu.tw
Key Words	Copy number alteration; High-density single nucleotide polymorphism arrays; Driver genes; Hepatocellular carcinoma
Core Tip	In addition to detecting somatic mutations in cancer genomes with high-throughput short-read sequencing technologies, analysis of copy number alteration in hepatocellular carcinoma (HCC) cancer genomes genotyped by high density single nucleotide polymorphism arrays is a cost-effective approach to reveal genome-wide somatic alterations accumulated during tumorigenesis. Integration with other genomic data from HCC tissues derived from high-throughput short-read sequencing, proteomics, epigenomics and transcriptomics could provide lines of evidence to identify common and novel HCC genes for potential clinical applications.
Publish Date	2014-01-20 16:41
Citation	Gu DL, Chen YH, Shih JH, Lin CH, Jou YS, Chen CF. Target genes discovery through copy number alteration analysis in human hepatocellular carcinoma. World J Gastroenterol 2013; 19(47): 8873-8879
URL	http://www.wjgnet.com/1007-9327/full/v19/i47/8873.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i47.8873

Full Article (PDF)	WJG-19-8873.pdf
Manuscript File	6029-Review.docx
Answering Reviewers	6029-Answering reviewers.pdf
Copyright License Agreement	6029-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	6029-Language certificate.pdf
Peer-review Report	6029-Peer review(s).pdf
Scientific Editor Work List	6029-Scientific editor work list.doc