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Articles Published Processes
2/20/2021 2:51:13 AM | Browse: 492 | Download: 1041
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Received |
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2020-10-27 01:45 |
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Peer-Review Started |
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2020-10-27 01:46 |
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To Make the First Decision |
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Return for Revision |
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2020-12-13 02:19 |
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Revised |
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2020-12-24 11:12 |
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Second Decision |
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2021-01-13 13:32 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-01-13 17:51 |
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Articles in Press |
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2021-01-13 17:51 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-01-27 05:29 |
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Typeset the Manuscript |
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2021-02-19 03:32 |
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Publish the Manuscript Online |
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2021-02-20 02:51 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Xiangbinfang granules enhance gastric antrum motility via intramuscular interstitial cells of Cajal in mice
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Qi-Cheng Chen, Zhi Jiang, Jun-Hong Zhang, Li-Xing Cao and Zhi-Qiang Chen |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Specific Research Fund for TCM Science and Technology of Guangdong Provincial Hospital of Chinese Medicine |
YN10101902 |
| National Regional Traditional Chinese Medicine (Specialist) Clinic Construction |
(2018)205 |
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| Corresponding Author |
Zhi-Qiang Chen, MD, Professor, The Research Team of TCM Applications of Perioperative, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Hospital of Traditional Chinese Medicine, No. 111 Dade Road, Guangzhou 510120, Guangdong Province, China. wssq@gzucm.edu.cn |
| Key Words |
Interstitial cells of Cajal; Migrating motor complex; W/Wv; Gastric antrum motility; Xiangbinfang granule; Chinese medicine |
| Core Tip |
This study shows that intramuscular interstitial cells of Cajal (ICC-IM) play crucial roles in regulating the gastric antral migrating motor complexes (MMC) activity. It may be an important bridge between vagus, the enteric nervous system and motilin to regulate smooth muscle contraction. Through the muscarinic receptor pathway on ICC-IM, the Chinese medicine Xiangbinfang granule depolarizes smooth muscle cells and initiates an action potential, changing the periodic motion of MMC into a phase III-like contractions pattern of gastric antrum in mice. |
| Publish Date |
2021-02-20 02:51 |
| Citation |
Chen QC, Jiang Z, Zhang JH, Cao LX, Chen ZQ. Xiangbinfang granules enhance gastric antrum motility via intramuscular interstitial cells of Cajal in mice. World J Gastroenterol 2021; 27(7): 576-591 |
| URL |
https://www.wjgnet.com/1007-9327/full/v27/i7/576.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v27.i7.576 |
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