Publication Name	World Journal of Gastroenterology
Manuscript ID	6035
Country	Italy

Received	2013-09-30 08:38
Peer-Review Started	2013-10-01 21:14
To Make the First Decision	2014-02-28 19:24
Return for Revision	2014-03-07 17:34
Revised	2013-12-23 19:00
Second Decision	2014-05-05 08:30
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-05-05 09:45
Articles in Press	2014-05-23 11:07
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-05-19 05:55
Typeset the Manuscript	2014-07-18 11:17
Publish the Manuscript Online	2014-08-07 10:34

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Surgery
Manuscript Type	Topic Highlights
Article Title	Relationship between pouch microbiota and pouchitis following restorative proctocolectomy for ulcerative colitis
Manuscript Source	Invited Manuscript
All Author List	Imerio Angriman, Marco Scarpa and Ignazio Castagliuolo
Funding Agency and Grant Number
Corresponding Author	Imerio Angriman, MD, Department of Surgery, Gastroenterology and Oncology, University of Padova, Via Giustiniani 2, 35128 Padova, Italy. imerio.angriman@unipd.it
Key Words	Pouchitis; Inflammation of the ileal pouch; Microbiota; Bacteria; Microbiome; Ileal-pouch-anal anastomosis; Ulcerative colitis; Crohn’s disease; Inflammatory bowel disease
Core Tip	This is a systemic review assessing the relationship between the microbiota that inhabit the ileal-anal pouch following restorative proctocolectomy in ulcerative colitis and familial adenomatous polyposis patients and the inflammatory response that can occur. A meta-analysis was not attempted in view of the highly heterogeneous microbiota composition and the different detection methods utilized. Although no specific bacterial species, genus, or family has as yet been identified as pathogenic, there is evidence that dysbiosis and reduced bacterial diversity of the microbiota found in ulcerative colitis patients who have undergone restorative proctocolectomy may, in genetically predisposed subjects, lead to aberrant mucosal immune regulation triggering an inflammatory process.
Publish Date	2014-08-07 10:34
Citation	Angriman I, Scarpa M, Castagliuolo I. Relationship between pouch microbiota and pouchitis following restorative proctocolectomy for ulcerative colitis. World J Gastroenterol 2014; 20(29): 9665-9674
URL	http://www.wjgnet.com/1007-9327/full/v20/i29/9665.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i29.9665

Full Article (PDF)	WJG-20-9665.pdf
Full Article (Word)	WJG-20-9665.doc
Manuscript File	6035-Review.doc
Answering Reviewers	6035-Answering reviewers.pdf
Copyright License Agreement	6035-Copyright assignment.pdf
Peer-review Report	6035-Peer review(s).pdf
Scientific Editor Work List	6035-Scientific editor work list.pdf