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8/25/2014 2:47:00 PM | Browse: 1011 | Download: 1027
Publication Name World Journal of Gastroenterology
Manuscript ID 6035
Country/Territory Italy
Received
2013-09-30 08:38
Peer-Review Started
2013-10-01 21:14
To Make the First Decision
2014-02-28 19:24
Return for Revision
2014-03-07 17:34
Revised
2013-12-23 19:00
Second Decision
2014-05-05 08:30
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-05-05 09:45
Articles in Press
2014-05-23 11:07
Publication Fee Transferred
Edit the Manuscript by Language Editor
2014-05-19 05:55
Typeset the Manuscript
2014-07-18 11:17
Publish the Manuscript Online
2014-08-07 10:34
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Surgery
Manuscript Type Topic Highlights
Article Title Relationship between pouch microbiota and pouchitis following restorative proctocolectomy for ulcerative colitis
Manuscript Source Invited Manuscript
All Author List Imerio Angriman, Marco Scarpa and Ignazio Castagliuolo
Funding Agency and Grant Number
Corresponding Author Imerio Angriman, MD, Department of Surgery, Gastroenterology and Oncology, University of Padova, Via Giustiniani 2, 35128 Padova, Italy. imerio.angriman@unipd.it
Key Words Pouchitis; Inflammation of the ileal pouch; Microbiota; Bacteria; Microbiome; Ileal-pouch-anal anastomosis; Ulcerative colitis; Crohn’s disease; Inflammatory bowel disease
Core Tip This is a systemic review assessing the relationship between the microbiota that inhabit the ileal-anal pouch following restorative proctocolectomy in ulcerative colitis and familial adenomatous polyposis patients and the inflammatory response that can occur. A meta-analysis was not attempted in view of the highly heterogeneous microbiota composition and the different detection methods utilized. Although no specific bacterial species, genus, or family has as yet been identified as pathogenic, there is evidence that dysbiosis and reduced bacterial diversity of the microbiota found in ulcerative colitis patients who have undergone restorative proctocolectomy may, in genetically predisposed subjects, lead to aberrant mucosal immune regulation triggering an inflammatory process.
Publish Date 2014-08-07 10:34
Citation Angriman I, Scarpa M, Castagliuolo I. Relationship between pouch microbiota and pouchitis following restorative proctocolectomy for ulcerative colitis. World J Gastroenterol 2014; 20(29): 9665-9674
URL http://www.wjgnet.com/1007-9327/full/v20/i29/9665.htm
DOI http://dx.doi.org/10.3748/wjg.v20.i29.9665
Full Article (PDF) WJG-20-9665.pdf
Full Article (Word) WJG-20-9665.doc
Manuscript File 6035-Review.doc
Answering Reviewers 6035-Answering reviewers.pdf
Copyright License Agreement 6035-Copyright assignment.pdf
Peer-review Report 6035-Peer review(s).pdf
Scientific Editor Work List 6035-Scientific editor work list.pdf