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Articles Published Processes
4/2/2021 12:29:13 PM | Browse: 492 | Download: 1183
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Received |
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2020-12-22 11:02 |
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Peer-Review Started |
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2020-12-22 11:02 |
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To Make the First Decision |
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Return for Revision |
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2021-01-10 21:22 |
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Revised |
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2021-01-12 18:32 |
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Second Decision |
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2021-01-30 13:43 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-02-01 19:52 |
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Articles in Press |
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2021-02-01 19:52 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-02-20 00:44 |
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Typeset the Manuscript |
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2021-03-03 00:57 |
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Publish the Manuscript Online |
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2021-04-02 12:29 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Pathology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Relationship between mismatch repair protein, RAS, BRAF, PIK3CA gene expression and clinicopathological characteristics in elderly colorectal cancer
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jun-Zhen Fan, Gao-Fei Wang, Xue-Bin Cheng, Zhou-Huan Dong, Xin Chen, Yu-Jiao Deng and Xin Song |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Xin Song, MM, Associate Chief Technician, Department of Pathology, First Medical Center, Chinese People's Liberation ArmyGeneral Hospital, No. 28 Fuxing Road, Haidian District, Beijing 100853, China. sxin66@hotmail.com |
| Key Words |
Elderly patients; Colorectal cancer; Mismatch repair protein; Gene mutation; Expression; Diagnosis |
| Core Tip |
The mismatch repair (MMR) protein deletion is one of the causes of colorectal cancer (CRC). The RAS (KRAS/NRAS), BRAF, and PIK3CA genes are important gene targets in CRC treatment and are closely related to the prognosis and survival of patients. However, the relationship between the expression of MMR, RAS, BRAF, PIK3CA and the clinicopathological features in CRC patients is still little known. In this study, we analyzed four target genes to provide a further theoretical basis for clinicians in the diagnosis, treatment and prognosis of CRC. |
| Publish Date |
2021-04-02 12:29 |
| Citation |
Fan JZ, Wang GF, Cheng XB, Dong ZH, Chen X, Deng YJ, Song X. Relationship between mismatch repair protein, RAS, BRAF, PIK3CA gene expression and clinicopathological characteristics in elderly colorectal cancer. World J Clin Cases 2021; 9(11): 2458-2468 |
| URL |
https://www.wjgnet.com/2307-8960/full/v9/i11/2458.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v9.i11.2458 |
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