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4/15/2021 4:26:47 AM | Browse: 371 | Download: 723
Publication Name World Journal of Clinical Cases
Manuscript ID 60790
Country China
Received
2020-11-18 08:03
Peer-Review Started
2020-11-16 08:33
To Make the First Decision
Return for Revision
2020-12-30 20:32
Revised
2021-01-13 08:08
Second Decision
2021-02-22 13:20
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-02-23 06:22
Articles in Press
2021-02-23 06:22
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-03-10 06:17
Typeset the Manuscript
2021-03-19 01:35
Publish the Manuscript Online
2021-04-15 04:26
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Case Report
Article Title Partial respond to Chinese patent medicine kangliu pill for adult glioblastoma: A case report and review of literature
Manuscript Source Unsolicited Manuscript
All Author List Ge Sun, Wei Zhuang, Qing-Tang Lin, Lei-Ming Wang, Yu-Hang Zhen, Sheng-Yan Xi and Xiao-Lan Lin
ORCID
Author(s) ORCID Number
Ge Sun http://orcid.org/0000-0002-2243-1683
Wei Zhuang http://orcid.org/0000-0003-3846-6351
Qing-Tang Lin http://orcid.org/0000-0002-0661-2951
Lei-Ming Wang http://orcid.org/0000-0002-8257-0175
Yu-Hang Zhen http://orcid.org/0000-0002-9348-1581
Sheng-Yan Xi http://orcid.org/0000-0002-8315-6742
Xiao-Lan Lin http://orcid.org/0000-0001-7033-2981
Funding Agency and Grant Number
Funding Agency Grant Number
The Foundation for Beijing Science and Technology Development of TCM JJ2016-10
The National Traditional Chinese Medicine Innovative Talents Training Project from Beijing Municipal Science and Technology Commission Z171100001717006
Corresponding Author Xiao-Lan Lin, N/A, Chief Pharmacist, Reader (Associate Professor), Department of Pharmacy, Xuanwu Hospital of Capital Medical University, No. 45, Changchun Street, Beijing 100053, China. xllin83@163.com
Key Words Glioblastoma; Kangliu Pill; Traditional Chinese medicine; Therapeutic effect; Adjunct therapy; Chinese patent medicine; Case report
Core Tip Glioblastoma is the most common type of malignant primary brain cancer. The standard treatment for newly diagnosed glioblastoma includes surgery followed by concurrent chemoradiotherapy and further adjuvant temozolomide. However, patients usually have a poor prognosis and high recurrence rate, and may develop drug resistance and serious adverse reactions to chemotherapy. Some recent studies suggested that traditional Chinese medicine may have a good therapeutic effect in patients with glioblastoma, and it is generally used as an adjunct therapy for various stages of tumors in clinical practice. In this case, we report a patient with glioblastoma who abandoned chemoradiotherapy because of intolerance, and subsequently received the Chinese patent medicine Kangliu pill without any other treatment. Three months after the start of treatment, the patient had a partial response, which persisted for more than 3 years. This surprising discovery indicates that the Chinese patent medicine Kangliu pill may provide a new option for the treatment of glioblastoma.
Publish Date 2021-04-15 04:26
Citation Sun G, Zhuang W, Lin QT, Wang LM, Zhen YH, Xi SY, Lin XL. Partial respond to chinese patent medicine kangliu pill for adult glioblastoma: A case report and review of literature. World J Clin Cases 2021; 9(12): 2845-2853
URL https://www.wjgnet.com/2307-8960/full/v9/i12/2845.htm
DOI https://dx.doi.org/10.12998/wjcc.v9.i12.2845
Full Article (PDF) WJCC-9-2845.pdf
Full Article (Word) WJCC-9-2845.docx
CARE Checklist–2016 60790-CARE-Checklist–2016-revision.pdf
Manuscript File 60790_Auto_Edited_LM-Webster J-Clear.docx
Answering Reviewers 60790-Answering reviewers.pdf
Audio Core Tip 60790-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 60790-Conflict-of-interest statement.pdf
Copyright License Agreement 60790-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 60790-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 60790-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate 60790-Language certificate.pdf
Peer-review Report 60790-Peer-review(s).pdf
Scientific Misconduct Check 60790-Bing-Yan JP-1.png
Scientific Misconduct Check 60790-Scientific misconduct check.pdf
Scientific Editor Work List 60790-Scientific editor work list.pdf