Publication Name	World Journal of Gastroenterology
Manuscript ID	6081
Country	China

Received	2013-10-01 19:30
Peer-Review Started	2013-10-01 21:28
To Make the First Decision	2013-10-22 16:17
Return for Revision	2013-10-23 19:34
Revised	2013-11-02 19:29
Second Decision	2014-02-20 09:06
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-02-20 09:30
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-03-19 21:22
Typeset the Manuscript	2014-04-16 11:16
Publish the Manuscript Online	2014-04-29 09:53

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Pharmacology & Pharmacy
Manuscript Type	Autobiography
Article Title	Hepatoprotective effect of Cichorium intybus L., a traditional Uighur medicine, against carbon tetrachloride-induced hepatic fibrosis in rats
Manuscript Source	Invited Manuscript
All Author List	Guo-Yu Li, Hong-Ying Gao, Jian Huang, Jin Lu, Jing-Kai Gu and Jin-Hui Wang
Funding Agency and Grant Number	Funding Agency Grant Number Key Projects of the National Science and Technology Pillar Program 2012BAI30B02
Corresponding Author	Jing-Kai Gu, PhD, Research Center for Drug Metabolism, College of Life Science, Jilin University, Qianjin Street, 9 Changchun 130012, Jilin Province, China. gujk@mail.jlu.edu.cn
Key Words	Cichorium intybus L. extract; Traditional Uighur medicine; Hepatic fibrosis; Carbon tetrachloride
Core Tip	Cichorium intybus L. extract (CIE) is a traditional Uighur medicine that is commonly used in China and other Asian countries to nourish and improve the liver. The present study demonstrated that CIE has a hepatoprotective effect against CCl4-induced hepatotoxicity in rats. We propose that the increased levels of antioxidant enzymes and reduced levels of malondialdehyde are the major mechanism of CIE for preventing the development of liver fibrosis induced by CCl4.
Publish Date	2014-04-29 09:53
Citation	Li GY, Gao HY, Huang J, Lu J, Gu JK, Wang JH. Hepatoprotective effect of Cichorium intybus L., a traditional Uighur medicine, against carbon tetrachloride-induced hepatic fibrosis in rats. World J Gastroenterol 2014; 20(16): 4753-4760
URL	http://www.wjgnet.com/1007-9327/full/v20/i16/4753.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i16.4753

Full Article (PDF)	WJG-20-4753.pdf
Full Article (Word)	WJG-20-4753.doc
Manuscript File	6081-Review.doc
Answering Reviewers	6081-Answering reviewers.pdf
Copyright License Agreement	6081-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	6081-Language certificate.pdf
Peer-review Report	6081-Peer review(s).pdf
Scientific Editor Work List	6081-Scientific editor work list.doc