| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Effect of liver inflammation on accuracy of FibroScan device in assessing liver fibrosis stage in patients with chronic hepatitis B virus infection
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ling-Ling Huang, Xue-Ping Yu, Ju-Lan Li, Hui-Ming Lin, Na-Ling Kang, Jia-Ji Jiang, Yue-Yong Zhu, Yu-Rui Liu and Da-Wu Zeng |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Science and Technology Department of Fujian Province, China |
2019Y0015 |
| Science and Technology Department of Fujian Province, China |
2019J01432 |
| Chinese National 13th Five-Year Plan's Science and Technology Projects |
2017ZX10202201 |
| Quanzhou Science and Technology Project of Fujian Province, China |
2018Z074 |
|
| Corresponding Author |
Da-Wu Zeng, MD, PhD, Associate Chief Physician, Doctor, Doctor, Department of Hepatology, Hepatology Research Institute, The First Affiliated Hospital, Fujian Medical University, No. 20 Chazhong Road, Taijiang District, Fuzhou 350005, Fujian Province, China. zengdw1980@fjmu.edu.cn |
| Key Words |
Liver stiffness measurement; Fibrosis stage; Liver inflammation; Hepatitis B virus; FibroScan; Predictive model |
| Core Tip |
Transient elastography (FibroScan) is a recommended non-invasive test for evaluation of liver fibrosis in patients with chronic hepatitis B virus (HBV) infection. In this study, we demonstrated the good performance of FibroScan in predicting liver fibrosis staging. However, we found that the discordance between Fibroscan fibrosis staging and pathological score. Liver inflammation was an independent risk factor affecting the accuracy of FibroScan assessing HBV related liver fibrosis staging. The combination of other related non-invasive factors can predict the risk of FibroScan staging misdiagnosis, and may be helpful for guiding the diagnosis and therapy of chronic HBV infection. |
| Publish Date |
2021-02-20 02:51 |
| Citation |
Huang LL, Yu XP, Li JL, Lin HM, Kang NL, Jiang JJ, Zhu YY, Liu YR, Zeng DW. Effect of liver inflammation on accuracy of FibroScan device in assessing liver fibrosis stage in patients with chronic hepatitis B virus infection. World J Gastroenterol 2021; 27(7): 641-653 |
| URL |
https://www.wjgnet.com/1007-9327/full/v27/i7/641.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v27.i7.641 |
