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Articles Published Processes
6/26/2021 7:48:02 AM | Browse: 469 | Download: 1086
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Received |
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2020-11-20 14:46 |
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Peer-Review Started |
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2020-11-20 14:47 |
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To Make the First Decision |
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Return for Revision |
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2020-12-21 03:48 |
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Revised |
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2020-12-22 18:39 |
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Second Decision |
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2021-01-06 03:36 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-02-02 03:22 |
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Articles in Press |
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2021-02-02 03:22 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-06-03 09:16 |
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Typeset the Manuscript |
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2021-06-23 14:00 |
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Publish the Manuscript Online |
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2021-06-26 07:48 |
ISSN |
1948-0210 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Hematology |
Manuscript Type |
Minireviews |
Article Title |
Growing and aging of hematopoietic stem cells
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Manuscript Source |
Invited Manuscript |
All Author List |
Ion Udroiu and Antonella Sgura |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Ion Udroiu, PhD, Research Fellow, Department of Science, Roma Tre University, Viale G. Marconi 446, Rome 00146, Italy. ion.udroiu@uniroma3.it |
Key Words |
Bone marrow; Fetus; Growth and development; Hematopoietic stem cells; Leukemia; Liver |
Core Tip |
During ontogeny, hematopoietic stem cells undergo a fetal and neonatal phase of rapid expansion. The kinetics of this growth are mirrored by the rates of telomere shortening in leukocytes. During adulthood, hematopoietic stem cells undergo a very small number of cell divisions. Nonetheless, they are subjected to aging, eventually reducing their potential to produce differentiated progeny. |
Publish Date |
2021-06-26 07:48 |
Citation |
Udroiu I, Sgura A. Growing and aging of hematopoietic stem cells. World J Stem Cells 2021; 13(6): 594-604 |
URL |
https://www.wjgnet.com/1948-0210/full/v13/i6/594.htm |
DOI |
https://dx.doi.org/10.4252/wjsc.v13.i6.594 |
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