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Articles Published Processes
6/7/2021 11:17:20 AM | Browse: 537 | Download: 1339
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Received |
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2021-01-27 01:00 |
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Peer-Review Started |
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2021-01-27 01:14 |
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To Make the First Decision |
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Return for Revision |
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2021-03-08 06:44 |
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Revised |
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2021-04-13 23:06 |
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Second Decision |
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2021-05-22 14:58 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-05-22 15:06 |
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Articles in Press |
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2021-05-22 15:06 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2021-05-31 01:01 |
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Publish the Manuscript Online |
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2021-06-07 11:17 |
ISSN |
1948-5204 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Observational Study |
Article Title |
Serum vascular endothelial growth factor as a tumor marker for hepatocellular carcinoma in hepatitis C virus-related cirrhotic patients
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Manuscript Source |
Invited Manuscript |
All Author List |
Ahmed Alzamzamy, Huda Elsayed, Mona Abd Elraouf, Hanan Eltoukhy, Tarek Megahed and Ashraf Aboubakr |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Ahmed Alzamzamy, MD, PhD, Lecturer, Department of Gastroenterology and Hepatology, Military Medical Academy, Ehsan Abdelkodous Street from Elkhalifa Elmaemoun Street, Heliopolis, Cairo 11841, Egypt. dr_zamzamy@hotmail.com |
Key Words |
Hepatocellular carcinoma; Vascular endothelial growth factor; Biomarkers; Diagnosis |
Core Tip |
We conducted an observational study with 100 patients to assess the usefulness of serum vascular endothelial growth factor (VEGF) and VEGF/platelet (PLT) as tumor markers for hepatocellular carcinoma (HCC) diagnosis in hepatitis C virus-related cirrhotic patients, and comparing them to serum alpha fetoprotein (AFP); the conventional marker of HCC. It was found that serum VEGF and VEGF/PLT appear to be additional diagnostic markers for HCC detection and prognostic markers during HCC patients follow up. Also, combined measurement of serum VEGF, VEGF/PLT and AFP significantly increase the sensitivity, specificity and accuracy in detection of HCC among cirrhotic patients rather than using of AFP, VEGF, or VEGF/PLT separately. |
Publish Date |
2021-06-07 11:17 |
Citation |
Alzamzamy A, Elsayed H, Abd Elraouf M, Eltoukhy H, Megahed T, Aboubakr A. Serum vascular endothelial growth factor as a tumor marker for hepatocellular carcinoma in hepatitis C virus-related cirrhotic patients. World J Gastrointest Oncol 2021; 13(6): 600-611 |
URL |
https://www.wjgnet.com/1948-5204/full/v13/i6/600.htm |
DOI |
https://dx.doi.org/10.4251/wjgo.v13.i6.600 |
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