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Articles Published Processes
4/8/2021 10:21:46 AM | Browse: 625 | Download: 1303
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Received |
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2020-11-22 03:54 |
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Peer-Review Started |
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2020-11-22 03:55 |
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To Make the First Decision |
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Return for Revision |
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2021-01-11 05:22 |
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Revised |
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2021-01-22 10:47 |
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Second Decision |
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2021-03-19 11:07 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-03-19 16:57 |
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Articles in Press |
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2021-03-19 16:57 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2021-03-29 13:17 |
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Publish the Manuscript Online |
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2021-04-08 10:21 |
| ISSN |
2220-3230 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Transplantation |
| Manuscript Type |
Minireviews |
| Article Title |
Does steroid-free immunosuppression improve the outcome in kidney transplant recipients compared to conventional protocols?
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Ahmed Aref, Ajay Sharma and Ahmed Halawa |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Ahmed Halawa, FRCS (Gen Surg), MSc, Surgeon, Department of Transplantation, Sheffield Teaching Hospitals, Herries Road, Sheffield S5 7AU, United Kingdom. ahmed.halawa@sth.nhs.uk |
| Key Words |
Kidney transplantation; Steroid free; Immune suppression; Steroid avoidance; Steroid withdrawal; Outcome |
| Core Tip |
Prolonged steroid therapy was associated with many complications that ranged from cosmetic changes to life-threatening increase in cardiovascular risk profile. The utilisation of antibody induction, together with calcineurin inhibitors maintenance immune suppression, had markedly reduced the incidence of acute rejection. The improved rate of acute rejection encouraged different transplant centres to adopt new steroid-free protocols, especially in fragile cases with multiple comorbidities. Variable steroid-free approaches were tried. We aim to explore the safety and efficacy of various steroid-free protocols by comparing each different modality with the conventional triple immune suppression. |
| Publish Date |
2021-04-08 10:21 |
| Citation |
Aref A, Sharma A, Halawa A. Does steroid-free immunosuppression improve the outcome in kidney transplant recipients compared to conventional protocols? World J Transplant 2021; 11(4): 99-113 |
| URL |
https://www.wjgnet.com/2220-3230/full/v11/i4/99.htm |
| DOI |
https://dx.doi.org/10.5500/wjt.v11.i4.99 |
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