Publication Name	World Journal of Hepatology
Manuscript ID	61093
Country	Egypt

Received	2020-11-23 16:24
Peer-Review Started	2020-11-23 16:24
To Make the First Decision
Return for Revision	2020-12-13 05:14
Revised	2020-12-14 18:17
Second Decision	2021-02-03 10:15
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2021-03-03 02:47
Articles in Press	2021-03-03 02:47
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2021-03-14 05:11
Publish the Manuscript Online	2021-03-20 02:13

ISSN	1948-5182 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Biochemistry & Molecular Biology
Manuscript Type	Basic Study
Article Title	Promotive action of 2-acetylaminofluorene on hepatic precancerous lesions initiated by diethylnitrosamine in rats: Molecular study
Manuscript Source	Invited Manuscript
All Author List	Amany Helmy Hasanin, Eman K Habib, Nesreen El Gayar and Marwa Matboli
ORCID	Author(s) ORCID Number Amany Helmy Hasanin http://orcid.org/0000-0002-8018-4350 Eman K Habib http://orcid.org/0000-0001-8899-6057 Nesreen El Gayar http://orcid.org/0000-0001-8591-3244 Marwa Matboli http://orcid.org/0000-0002-6852-3954
Funding Agency and Grant Number
Corresponding Author	Marwa Matboli, MD, Adjunct Professor, Associate Professor, Medical Biochemistry and Molecular Biology Department, Faculty of Medicine, Ain Shams University, Abbassia, P.O. box 11381, Cairo 11381, Egypt. marwasayed472@yahoo.com
Key Words	Acetylaminofluorene; Hepatic precancerous lesion; Diethylnitrosamine; Autophagy; Apoptosis; MicroRNA
Core Tip	2-Acetylaminofluorene epigenetically regulated the expression of long-noncoding RNA RP11-513I15.6/miRNA-1262/miR-1298 (microRNA, miRNA) resulted in decrease in RAB11A, BAX, and p53 mRNA, and the increase in Cyclin E mRNA leading to increased hepatocyte proliferation and decreased apoptosis promoting hepatocellular promoted precancerous lesion in rat models.
Publish Date	2021-03-20 02:13
Citation	Hasanin AH, Habib EK, El Gayar N, Matboli M. Promotive action of 2-acetylaminofluorene on hepatic precancerous lesions initiated by diethylnitrosamine in rats: Molecular study. World J Hepatol 2021; 13(3): 328-342
URL	https://www.wjgnet.com/1948-5182/full/v13/i3/328.htm
DOI	https://dx.doi.org/10.4254/wjh.v13.i3.328

Full Article (PDF)	WJH-13-328.pdf
Full Article (Word)	WJH-13-328.docx
Manuscript File	61093_Auto_Edited_LM.docx
Answering Reviewers	61093-Answering reviewers.pdf
Audio Core Tip	61093-Audio core tip.wav
Biostatistics Review Certificate	61093-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	61093-Conflict-of-interest statement.pdf
Copyright License Agreement	61093-Copyright license agreement.pdf
Institutional Animal Care and Use Committee Approval Form or Document	61093-Institutional animal care and use committee statement.pdf
Non-Native Speakers of English Editing Certificate	61093-Language certificate.pdf
Peer-review Report	61093-Peer-review(s).pdf
Scientific Misconduct Check	61093-Bing-Fan JR-1.png
Scientific Misconduct Check	61093-Scientific misconduct check.pdf
Scientific Editor Work List	61093-Scientific editor work list.pdf
CrossCheck Report	61093-CrossCheck report.pdf