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5/26/2021 9:58:01 AM | Browse: 306 | Download: 1161
Publication Name World Journal of Clinical Cases
Manuscript ID 61125
Country/Territory Russia
Received
2021-01-09 13:51
Peer-Review Started
2021-01-09 13:52
To Make the First Decision
Return for Revision
2021-01-30 14:28
Revised
2021-02-12 18:14
Second Decision
2021-04-22 12:39
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-04-22 13:21
Articles in Press
2021-04-22 13:21
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2021-05-19 01:55
Publish the Manuscript Online
2021-05-26 09:58
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Observational Study
Article Title Patients with functional bowel disorder have disaccharidase deficiency: A single-center study from Russia
Manuscript Source Invited Manuscript
All Author List Saria Dbar, Olga Akhmadullina, Elena Sabelnikova, Nikolai Belostotskiy, Asfold Parfenov, Svetlana Bykova, Sergey Bakharev, Elena Baulo, Alexandra Babanova, Lilia Indeykina, Tatyana Kuzmina, Tatiana Kosacheva, Aleksey Spasenov and Alina Makarova
ORCID
Author(s) ORCID Number
Saria Dbar http://orcid.org/0000-0001-6516-7782
Olga Akhmadullina http://orcid.org/0000-0002-4010-6761
Elena Sabelnikova http://orcid.org/0000-0001-7519-2041
Nikolai Belostotskiy http://orcid.org/0000-0003-4400-1227
Asfold Parfenov http://orcid.org/0000-0002-9782-4860
Svetlana Bykova http://orcid.org/0000-0001-9576-2953
Sergey Bakharev http://orcid.org/0000-0003-2213-6147
Elena Baulo http://orcid.org/0000-0002-8300-7608
Alexandra Babanova http://orcid.org/0000-0001-9263-8324
Lilia Indeykina http://orcid.org/0000-0002-3829-3211
Tatyana Kuzmina http://orcid.org/0000-0003-2800-6503
Tatiana Kosacheva http://orcid.org/0000-0002-4951-0605
Aleksey Spasenov http://orcid.org/0000-0001-7492-7966
Alina Makarova http://orcid.org/0000-0003-1050-2437
Funding Agency and Grant Number
Corresponding Author Saria Dbar, MD, Academic Fellow, Non-inflammatory Bowel Diseases, Moscow Health Department, Moscow Clinical Scientific Center n.a. A.S. Loginov, Shosse Entuziastov 86, Build 1, Moscow 111123, Russia. saradbar@yandex.ru
Key Words Functional bowel disorder; Irritable bowel syndrome; Disaccharidase deficiency; Maltase deficiency; Sucrase deficiency; Lactase deficiency
Core Tip Our study has shown that patients with functional bowel disorders (FBDs) often had a deficiency of intestinal enzymes. We supposed that there can be a different mechanism for developing FBD: a damage of the small intestine mucous membrane may result in a decreased activity of the enzymes on the brush border of enterocytes, which leads to the disorder of carbohydrates' hydrolysis and the accumulation of osmoactive substances in the lumen of the small intestine, in its turn it causes a bacterial overgrowth in the small intestine, stool disorder, abdominal pain and bloating. The timely diagnosis of disaccharidase deficiency could lead to a better prognosis in patients with FBD.
Publish Date 2021-05-26 09:58
Citation Dbar S, Akhmadullina O, Sabelnikova E, Belostotskiy N, Parfenov A, Bykova S, Bakharev S, Baulo E, Babanova A, Indeykina L, Kuzmina T, Kosacheva T, Spasenov A, Makarova A. Patients with functional bowel disorder have disaccharidase deficiency: A single-center study from Russia. World J Clin Cases 2021; 9(17): 4178-4187
URL https://www.wjgnet.com/2307-8960/full/v9/i17/4178.htm
DOI https://dx.doi.org/10.12998/wjcc.v9.i17.4178
Full Article (PDF) WJCC-9-4178.pdf
Full Article (Word) WJCC-9-4178.docx
Manuscript File 61125_Auto_Edited-ZMG.docx
Answering Reviewers 61125-Answering reviewers.pdf
Audio Core Tip 61125-Audio core tip.m4a
Biostatistics Review Certificate 61125-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 61125-Conflict-of-interest statement.pdf
Copyright License Agreement 61125-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 61125-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 61125-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 61125-Language certificate.pdf
Peer-review Report 61125-Peer-review(s).pdf
Scientific Misconduct Check 61125-Bing-Wang JL-1.jpg
Scientific Misconduct Check 61125-Scientific misconduct check.pdf
Scientific Editor Work List 61125-Scientific editor work list.pdf