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Articles Published Processes
2/4/2021 1:19:45 PM | Browse: 517 | Download: 1360
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Received |
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2020-11-24 22:08 |
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Peer-Review Started |
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2020-11-24 22:08 |
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To Make the First Decision |
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Return for Revision |
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2020-12-20 03:33 |
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Revised |
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2021-01-02 20:40 |
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Second Decision |
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2021-01-12 00:50 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-01-21 20:50 |
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Articles in Press |
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2021-01-21 20:50 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2021-02-01 05:58 |
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Publish the Manuscript Online |
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2021-02-04 13:19 |
ISSN |
1948-9366 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Surgery |
Manuscript Type |
Retrospective Cohort Study |
Article Title |
Colorectal cancer of the young displays distinct features of aggressive tumor biology: A single-center cohort study
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Matteo Mueller, Marcel André Schneider, Barla Deplazes, Daniela Cabalzar-Wondberg, Andreas Rickenbacher and Matthias Turina |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Matthias Turina, MD, PhD, Professor, Department of Surgery and Transplantation, University Hospital Zurich, Raemistrasse 100, Zurich 8091, Switzerland. matthias.turina@usz.ch |
Key Words |
Young-onset colorectal cancer; Tumor biology; Colorectal surgery; Tumor aggressiveness; Colorectal cancer; Colorectal cancer screening |
Core Tip |
We evaluated differences in tumor biology between young-onset colorectal cancer patients (< 50 years of age) and late-onset colorectal cancer (CRC) patients (≥ 50 years of age) in a Swiss tertiary cancer center over a six-year period. Parameters of interest included clinical as well as histopathological characteristics. This study reports a surprisingly high rate of CRC of young-onset, while affected patients present more frequently with locally advanced tumors, lymphatic invasion and with more frequent lymphatic metastases. This work puts cancer incidence in relation to histopathological details, mutational status, surgical parameters and selected risk factors. |
Publish Date |
2021-02-04 13:19 |
Citation |
Mueller M, Schneider MA, Deplazes B, Cabalzar-Wondberg D, Rickenbacher A, Turina M. Colorectal cancer of the young displays distinct features of aggressive tumor biology: A single-center cohort study. World J Gastrointest Surg 2021; 13(2): 164-175 |
URL |
https://www.wjgnet.com/1948-9366/full/v13/i2/164.htm |
DOI |
https://dx.doi.org/10.4240/wjgs.v13.i2.164 |
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