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Articles Published Processes
2/5/2021 10:20:18 AM | Browse: 542 | Download: 1360
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Received |
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2020-11-29 10:43 |
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Peer-Review Started |
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2020-11-29 10:43 |
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To Make the First Decision |
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Return for Revision |
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2020-12-08 02:26 |
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Revised |
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2020-12-20 07:37 |
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Second Decision |
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2021-01-12 12:06 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-01-12 18:36 |
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Articles in Press |
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2021-01-12 18:36 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-01-24 08:24 |
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Typeset the Manuscript |
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2021-01-28 07:01 |
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Publish the Manuscript Online |
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2021-02-05 10:20 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Retrospective Study |
Article Title |
Washed microbiota transplantation reduces proton pump inhibitor dependency in nonerosive reflux disease
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Ya-Mei Zheng, Xian-Yun Chen, Jie-Yi Cai, Yu Yuan, Wen-Rui Xie, Jia-Ting Xu, Harry Hua-Xiang Xia, Min Zhang, Xing-Xiang He and Li-Hao Wu |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Li-Hao Wu, MD, Associate Professor, Department of Gastroenterology, The First Affiliated Hospital of Guangdong Pharmaceutical University, Research Center for Engineering Techniques of Microbiota-Targeted Therapies of Guangdong Province, No. 19 Nonglinxia Road, Yuexiu District, Guangzhou 510030, Guangdong Province, China. wulihao888@126.com |
Key Words |
Nonerosive reflux disease; Washed microbiota transplantation; Proton pump inhibitor dependency; Intestinal bacteria; Lipopolysaccharide; Small intestinal bacterial overgrowth |
Core Tip |
In this study, we demonstrate for the first time that washed microbiota transplantation (WMT) is safe and effective for treating patients with nonerosive reflux disease (NERD) and proton pump inhibitor (PPI) dependency compared with PPI treatment. WMT significantly relieved the symptoms of NERD in patients, reduced PPI dependency, prolonged the duration of symptom remission and reduced symptom recurrence. |
Publish Date |
2021-02-05 10:20 |
Citation |
Zheng YM, Chen XY, Cai JY, Yuan Y, Xie WR, Xu JT, Xia HHX, Zhang M, He XX, Wu LH. Washed microbiota transplantation reduces proton pump inhibitor dependency in nonerosive reflux disease. World J Gastroenterol 2021; 27(6): 513-522 |
URL |
https://www.wjgnet.com/1007-9327/full/v27/i6/513.htm |
DOI |
https://dx.doi.org/10.3748/wjg.v27.i6.513 |
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