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Articles Published Processes
3/18/2021 9:01:27 AM | Browse: 583 | Download: 1065
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Received |
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2020-12-11 14:49 |
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Peer-Review Started |
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2020-12-11 14:50 |
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To Make the First Decision |
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Return for Revision |
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2021-01-11 04:04 |
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Revised |
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2021-01-17 08:20 |
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Second Decision |
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2021-02-20 06:41 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-03-03 02:50 |
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Articles in Press |
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2021-03-03 02:50 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2021-03-17 02:07 |
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Publish the Manuscript Online |
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2021-03-18 09:01 |
| ISSN |
1948-9366 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Review |
| Article Title |
Gastroenteropancreatic neuroendocrine neoplasms: A clinical snapshot
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Cornelius J Fernandez, Mayuri Agarwal, Biju Pottakkat, Nisha Nigil Haroon, Annu Susan George and Joseph M Pappachan |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Joseph M Pappachan, FRCP (Hon), MD, MRCP, Consultant Physician-Scientist, Senior Researcher, Department of Endocrinology and Metabolism, Lancashire Teaching Hospitals NHS Trust, The University of Manchester and Manchester Metropolitan University, All Saints Building M15 6BH, Oxford Road M13 9PL, Preston and Manchester PR2 9HT, United Kingdom. drpappachan@yahoo.co.in |
| Key Words |
Gastroenteropancreatic neuroendocrine neoplasms; Neuroendocrine tumours; Neuroendocrine carcinoma; Targeted molecular therapy; Octreoscan; Chemotherapy |
| Core Tip |
Gut, the largest endocrine organ of the body, secretes several hormones through its specialised neuroendocrine cells. Neuroendocrine neoplasms (NENs) originating from these cells are collectively known as gastroenteropancreatic (GEP) NENs that pose significant challenges to clinicians in the diagnostic work up, prognostication and management. Rapid advancements in the molecular diagnostic and therapeutic strategies in the recent years revolutionised the options for clinical investigations and management of patients with these uncommon neoplasms. This review updates the pathophysiological aspects, diagnostic strategies, and management algorithms of GEP NENs with the best evidence currently available in the global scientific literature to enable clinicians to optimally manage these unusual disease entities. |
| Publish Date |
2021-03-18 09:01 |
| Citation |
Fernandez CJ, Agarwal M, Pottakkat B, Haroon NN, George AS, Pappachan JM. Gastroenteropancreatic neuroendocrine neoplasms: A clinical snapshot. World J Gastrointest Surg 2021; 13(3): 231-255 |
| URL |
https://www.wjgnet.com/1948-9366/full/v13/i3/231.htm |
| DOI |
https://dx.doi.org/10.4240/wjgs.v13.i3.231 |
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