BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
3/11/2021 8:31:02 AM | Browse: 503 | Download: 907
 |
Received |
|
2020-12-12 17:14 |
|
Peer-Review Started |
|
2020-12-12 17:18 |
 |
To Make the First Decision |
|
|
|
Return for Revision |
|
2020-12-27 20:40 |
|
Revised |
|
2021-01-03 09:48 |
|
Second Decision |
|
2021-02-08 08:33 |
|
Accepted by Journal Editor-in-Chief |
|
|
|
Accepted by Executive Editor-in-Chief |
|
2021-02-11 17:42 |
|
Articles in Press |
|
2021-02-11 17:42 |
|
Publication Fee Transferred |
|
|
|
Edit the Manuscript by Language Editor |
|
2021-02-24 07:58 |
|
Typeset the Manuscript |
|
2021-03-09 08:05 |
|
Publish the Manuscript Online |
|
2021-03-11 08:31 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Opinion Review |
| Article Title |
Use of granulocyte/monocytapheresis in ulcerative colitis: A practical review from a European perspective
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Eugeni Domènech, Joan-Ramon Grífols, Ayesha Akbar and Axel U Dignass |
| ORCID |
|
| Funding Agency and Grant Number |
|
| Corresponding Author |
Eugeni Domènech, MD, PhD, Chief Physician, Professor, Department of Gastroenterology, Hospital Universitari Germans Trias i Pujol, Carretera del Canyet s/n, Badalona 08916, Catalonia, Spain. eugenidomenech@gmail.com |
| Key Words |
Granulocyte; Monocyte; Ulcerative colitis; Inflammatory bowel disease; Apheresis; Safety |
| Core Tip |
About 30%-40% of patients with ulcerative colitis will require immunosuppressive therapies, including immunomodulators and biological agents. Unfortunately, none of these therapies achieves more than 40% of steroid-free clinical remission in the middle term; moreover, most immunosuppressive therapies increase the risk of infections and some malignancies, raising the unmet need for therapeutic alternatives in ulcerative colitis. Granulocyte/monocytapheresis (GMA) remains the only therapy targeting neutrophils, the hallmark of pathology in ulcerative colitis. GMA has proven its efficacy in different clinical scenarios and shows an excellent and unique safety profile. |
| Publish Date |
2021-03-11 08:31 |
| Citation |
Domènech E, Grífols JR, Akbar A, Dignass AU. Use of granulocyte/monocytapheresis in ulcerative colitis: A practical review from a European perspective. World J Gastroenterol 2021; 27(10): 908-918 |
| URL |
https://www.wjgnet.com/1007-9327/full/v27/i10/908.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v27.i10.908 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
