Publication Name	World Journal of Clinical Cases
Manuscript ID	61784
Country	Greece

Received	2020-12-19 16:26
Peer-Review Started	2020-12-19 16:27
To Make the First Decision
Return for Revision	2021-01-10 16:08
Revised	2021-01-16 14:15
Second Decision	2021-03-18 07:02
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-03-18 23:24
Articles in Press	2021-03-18 23:24
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2021-03-25 01:14
Publish the Manuscript Online	2021-04-15 04:26

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Endocrinology & Metabolism
Manuscript Type	Minireviews
Article Title	Polycystic ovary syndrome: Pathways and mechanisms for possible increased susceptibility to COVID-19
Manuscript Source	Invited Manuscript
All Author List	Ioannis Ilias, Spyridon Goulas and Lina Zabuliene
ORCID	Author(s) ORCID Number Ioannis Ilias http://orcid.org/0000-0001-5718-7441 Spyridon Goulas http://orcid.org/0000-0002-1936-9014 Lina Zabuliene http://orcid.org/0000-0002-7889-0862
Funding Agency and Grant Number
Corresponding Author	Ioannis Ilias, MD, PhD, Consultant Physician-Scientist, Department of Endocrinology, Elena Venizelou Hospital, 2 Elena Venizelou Sq, Athens GR-11521, Greece. iiliasmd@yahoo.com
Key Words	Adipose tissue; Obesity; Polycystic ovaries; SARS-CoV-2; COVID-19; Human
Core Tip	Polycystic ovary syndrome (PCOS) may entail higher susceptibility to coronavirus disease 2019 (COVID-19). Furthermore, PCOS may also increase susceptibility to COVID-19 via its associated comorbidities (non-alcoholic fatty liver disease, metabolic syndrome and alterations in the gut microbiome). In order to determine whether the intestinal microbiome in women with PCOS has an effect on their risk of COVID-19 or if severe acute respiratory syndrome coronavirus 2 is the factor that changes the composition of their microbiome, more research will be needed. Strategies for adapting the intestinal microbiome could help reduce the severity of COVID-19 in women with PCOS.
Publish Date	2021-04-15 04:26
Citation	Ilias I, Goulas S, Zabuliene L. Polycystic ovary syndrome: Pathways and mechanisms for possible increased susceptibility to COVID-19. World J Clin Cases 2021; 9(12): 2711-2720
URL	https://www.wjgnet.com/2307-8960/full/v9/i12/2711.htm
DOI	https://dx.doi.org/10.12998/wjcc.v9.i12.2711

Full Article (PDF)	WJCC-9-2711.pdf
Full Article (Word)	WJCC-9-2711.docx
Manuscript File	61784_Auto_Edited.doc
Answering Reviewers	61784-Answering reviewers.pdf
Audio Core Tip	61784-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	61784-Conflict-of-interest statement.pdf
Copyright License Agreement	61784-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	61784-Language certificate.pdf
Peer-review Report	61784-Peer-review(s).pdf
Scientific Misconduct Check	61784-Bing-Gao CC-1.jpg
Scientific Misconduct Check	61784-Bing-Fan JR-2.png
Scientific Misconduct Check	61784-Scientific misconduct check.pdf
Scientific Editor Work List	61784-Scientific editor work list.pdf