Publication Name	World Journal of Cardiology
Manuscript ID	6184
Country	Finland

Received	2013-10-08 08:51
Peer-Review Started	2013-10-08 22:00
To Make the First Decision	2013-11-19 13:02
Return for Revision	2013-11-20 18:19
Revised	2013-11-29 19:28
Second Decision	2013-12-19 13:03
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2013-12-19 13:30
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-01-26 17:06
Publish the Manuscript Online	2014-01-27 10:56

ISSN	1949-8462 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Cardiac & Cardiovascular Systems
Manuscript Type	Minireviews
Article Title	Physiology of natriuretic peptides: The volume overload hypothesis revisited
Manuscript Source	Invited Manuscript
All Author List	Olli Arjamaa, MD, PhD, Senior Scientist, Department of Biology, University of Turku, Vesilinnanmäki, 20014 Turku and Finland. olli.arjamaa@utu.fi
Funding Agency and Grant Number
Corresponding Author	Olli Arjamaa, MD, PhD Department of Biology, 20014 University of Turku, Finland olli.arjamaa@utu.fi +358 40 5125452
Key Words	Natriuretic peptides; Hypoxia; Hemoglobin concentration; Volume overload
Core Tip	A new concept is suggested for the understanding of the physiology of natriuretic peptides. Both chemical and physical challenges will ultimately increase the oxygen consumption of the heart which is the factor regulating the release of natriuretic peptides. Diuresis, natriuresis and plasma shift lead to hemoconcentration and the oxygen transport in human body will be enhanced.
Publish Date	2014-01-27 10:56
Citation	Arjamaa O. Physiology of natriuretic peptides: The volume overload hypothesis revisited. World J Cardiol 2014; 6(1): 4-7 Available from: URL: http://www.wjgnet.com/1949-8462/full/ v6/i1/4.htm DOI: http://dx.doi.org/10.4330/wjc.v6.i1.4
URL	http://www.wjgnet.com/1949-8462/full/v6/i1/4.htm
DOI	http://dx.doi.org/10.4330/wjc.v6.i1.4

Full Article (PDF)	WJC-6-4.pdf
Full Article (Word)	WJC-6-4.doc
Manuscript File	6184-review.doc
Answering Reviewers	6184-Answering reviewers.pdf
Copyright License Agreement	6184-Copyright assignment.pdf
Peer-review Report	6184-Peer review(s).pdf
Scientific Editor Work List	6184-Scientific editor work list.doc