| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Biomarkers for hepatocellular carcinoma based on body fluids and feces
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Ming-Cheng Guan, Wei Ouyang, Ming-Da Wang, Lei Liang, Na Li, Ting-Ting Fu, Feng Shen, Wan-Yee Lau, Qiu-Ran Xu, Dong-Sheng Huang, Hong Zhu and Tian Yang |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81972726 |
| National Natural Science Foundation of China |
81871949 |
| National Natural Science Foundation of China |
81572345 |
|
| Corresponding Author |
Tian Yang, MD, Doctor, Doctor, Department of Hepatobiliary Surgery, Eastern Hepatobiliary Surgery Hospital (Navy Medical University), Second Military Medical University, No. 225 Changhai Road, Shanghai 200438, China. yangtian6666@hotmail.com |
| Key Words |
Hepatocellular carcinoma; Biomarker; Blood; Urine; Feces; Gut microbiota |
| Core Tip |
Hepatocellular carcinoma is the most frequently diagnosed malignancy of the liver, ranking as the fourth leading cause of cancer-related mortality worldwide. Recent developments of multiple novel biomarkers from body fluids and feces facilitate diagnosis and management of hepatocellular carcinoma. This review aimed to focus on these blood-, urine- and feces-based biomarkers including proteins, metabolites, circulating nucleic acids, circulating tumor cells, extracellular vesicles, and gut microbiota on clinical application of these biomarkers. |
| Publish Date |
2021-05-07 09:15 |
| Citation |
Guan MC, Ouyang W, Wang MD, Liang L, Li N, Fu TT, Shen F, Lau WY, Xu QR, Huang DS, Zhu H, Yang T. Biomarkers for hepatocellular carcinoma based on body fluids and feces. World J Gastrointest Oncol 2021; 13(5): 351-365 |
| URL |
https://www.wjgnet.com/1948-5204/full/v13/i5/351.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v13.i5.351 |
