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Articles Published Processes
3/30/2021 8:56:51 AM | Browse: 585 | Download: 1000
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Received |
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2020-12-21 21:21 |
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Peer-Review Started |
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2020-12-21 21:23 |
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To Make the First Decision |
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Return for Revision |
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2020-12-30 18:29 |
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Revised |
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2021-01-04 19:30 |
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Second Decision |
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2021-01-25 10:09 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-01-26 17:08 |
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Articles in Press |
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2021-01-26 17:08 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-01-30 22:24 |
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Typeset the Manuscript |
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2021-03-26 07:34 |
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Publish the Manuscript Online |
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2021-03-30 08:56 |
ISSN |
2307-8960 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Hematology |
Manuscript Type |
Case Report |
Article Title |
Acquired haemophilia in patients with malignant disease: A case report
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Veronika Krašek, Aleša Kotnik, Hana Zavrtanik, Jasna Klen and Samo Zver |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Hana Zavrtanik, MD, Doctor, Doctor, Department of Abdominal Surgery, University Medical Centre Ljubljana, Zaloška cesta 7, Ljubljana 1000, Slovenia. hana.zavrtanik@kclj.si |
Key Words |
Malignancy; Haemostasis; Bleeding diathesis; Eradication therapy; Case report |
Core Tip |
Acquired haemophilia is a rare coagulation disorder characterized by autoantibodies against coagulation factor VII. Patients present with different haemorrhagic symptoms usually to General or Emergency Physicians who might not be familiar with the disease. Whenever an unusual pattern of bleeding is observed in a patient, a bleeding disorder should be suspected. Immediate consultation with a reference haemophilia centre should be made for obtaining early diagnosis and treatment. In patients with cancer, a wide range of haemostatic disorders should be taken into consideration and distinguished from acquired haemophilia. Although invasive procedures should be avoided in patients with acquired haemophilia, surgical resection of the underlying malignancy is sometimes required. This subset of patients represents a treatment challenge not solely due to increased risk of bleeding but also due to adverse events of immunosuppressive therapy. |
Publish Date |
2021-03-30 08:56 |
Citation |
Krašek V, Kotnik A, Zavrtanik H, Klen J, Zver S. Acquired haemophilia in patients with malignant disease: A case report. World J Clin Cases 2021; 9(10): 2409-2418 |
URL |
https://www.wjgnet.com/2307-8960/full/v9/i10/2409.htm |
DOI |
https://dx.doi.org/10.12998/wjcc.v9.i10.2409 |
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