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Articles Published Processes
4/9/2021 9:07:56 AM | Browse: 389 | Download: 1043
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Received |
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2020-12-22 06:41 |
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Peer-Review Started |
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2020-12-22 06:42 |
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To Make the First Decision |
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Return for Revision |
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2021-01-17 03:02 |
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Revised |
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2021-01-22 19:29 |
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Second Decision |
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2021-03-25 12:38 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-03-26 16:11 |
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Articles in Press |
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2021-03-26 16:11 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2021-04-01 08:30 |
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Publish the Manuscript Online |
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2021-04-09 09:07 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Biochemistry & Molecular Biology |
| Manuscript Type |
Basic Study |
| Article Title |
Cyanidin 3-glucoside modulated cell cycle progression in liver precancerous lesion, in vivo study
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Marwa Matboli, Amany H Hasanin, Reham Hussein, Sarah El-Nakeep, Eman K Habib, Rawan Ellackany and Lobna A Saleh |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Marwa Matboli, MD, Associate Professor, Department of Biochemistry, Ain Shams Faculty of Medicine, Abassia Marg, Cairo 11318, Egypt. marwasayed472@yahoo.com |
| Key Words |
Hepatocellular carcinoma therapy; Hepatocellular-carcinoma growth; Hepatocellular-carcinoma model; Hepatocellular-carcinoma size |
| Core Tip |
Several regulatory RNA networks are important in regulation of liver cell cycle progression and are linked to the pathogenesis of hepatocellular carcinoma. Identification of critical steps involved in hepatocarcinogenesis are likely to lead to the development of new therapeutics that will inhibit tumor proliferation alongside with verification of promising drug targets biomarkers that may lead to improved patient survival. Cyanidin-3-O-glucoside (cyan) has a significant antioxidant and anticancer activities. Cyan could be used as potential agent to inhibit liver carcinogenesis in rat model via modulation of cell cycle. Cyan dose dependently decreased the long non-coding RNA-MALAT1 and TUBG1 mRNA expressions and increased the hsa-miR-125b expression which participate in cell cycle and mitotic spindle assembly. |
| Publish Date |
2021-04-09 09:07 |
| Citation |
Matboli M, Hasanin AH, Hussein R, El-Nakeep S, Habib EK, Ellackany R, Saleh LA. Cyanidin 3-glucoside modulated cell cycle progression in liver precancerous lesion, in vivo study. World J Gastroenterol 2021; 27(14): 1435-1450 |
| URL |
https://www.wjgnet.com/1007-9327/full/v27/i14/1435.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v27.i14.1435 |
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