ISSN |
2220-6124 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Cardiac & Cardiovascular Systems |
Manuscript Type |
Observational Study |
Article Title |
Low-molecular-weight dextran for optical coherence tomography may not be protective against kidney injury in patients with renal insufficiency
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Manuscript Source |
Invited Manuscript |
All Author List |
Toru Misawa, Tomoyo Sugiyama, Yoshihisa Kanaji, Masahiro Hoshino, Masao Yamaguchi, Masahiro Hada, Tatsuhiro Nagamine, Kai Nogami, Yumi Yasui, Eisuke Usui, Tetsumin Lee, Taishi Yonetsu, Tetsuo Sasano and Tsunekazu Kakuta |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Tsunekazu Kakuta, MD, PhD, Doctor, Doctor, Department of Cardiovascular Medicine, Tsuchiura Kyodo General Hospital, 4-1-1 Otsuno, Tsuchiura 300-0028, Ibaraki, Japan. kaz@joy.email.ne.jp |
Key Words |
Coronary artery disease; Kidney injury; Contrast media; Dextran; Optical coherence tomography; Renal insufficiency |
Core Tip |
Low-molecular-weight dextran (LMWD) is considered a safe alternative to contrast during optical coherence tomography (OCT) imaging. We evaluated differences between patients who used additional LMWD for OCT (LMWD group) and those who used contrast exclusively (Contrast group) and performed a propensity score-matched subgroup comparison. The LMWD group demonstrated a strong trend toward the progression of renal insufficiency during the 1-year follow-up. Propensity score-matched analyses indicated a trend toward worsening renal function in the LMWD group at the 1-year follow-up. Additional use of LMWD for OCT may not be protective against worsening renal function in patients with advanced renal insufficiency. |
Publish Date |
2021-03-18 03:01 |
Citation |
Misawa T, Sugiyama T, Kanaji Y, Hoshino M, Yamaguchi M, Hada M, Nagamine T, Nogami K, Yasui Y, Usui E, Lee T, Yonetsu T, Sasano T, Kakuta T. Low-molecular-weight dextran for optical coherence tomography may not be protective against kidney injury in patients with renal insufficiency. World J Nephrol 2021; 10(2): 8-20 |
URL |
https://www.wjgnet.com/2220-6124/full/v10/i2/8.htm |
DOI |
https://dx.doi.org/10.5527/wjn.v10.i2.8 |