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Articles Published Processes
6/11/2021 9:22:17 AM | Browse: 410 | Download: 979
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Received |
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2021-01-14 08:03 |
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Peer-Review Started |
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2021-01-14 08:05 |
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To Make the First Decision |
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Return for Revision |
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2021-03-16 11:53 |
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Revised |
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2021-03-27 10:40 |
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Second Decision |
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2021-04-22 12:42 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-04-22 13:29 |
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Articles in Press |
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2021-04-22 13:29 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-05-05 10:52 |
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Typeset the Manuscript |
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2021-06-01 05:18 |
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Publish the Manuscript Online |
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2021-06-11 09:22 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Tetramethylpyrazine inhibits proliferation of colon cancer cells in vitro
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hua Li, Yan-Xu Hou, Yu Yang, Qing-Qiang He, Tian-Hua Gao, Xiao-Feng Zhao, Zhi-Bin Huo, Shu-Bo Chen and Deng-Xiang Liu |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Deng-Xiang Liu, PhD, Academic Research, Chief Doctor, Institute of Cancer Control, Xing Tai People Hospital, No. 16 Hongxing Street, Xingtai 054001, Hebei Province, China. dengxianglfangliao@163.com |
| Key Words |
Tetramethylpyrazine; Colon cancer; Apoptosis; Cell proliferation; Chemotherapy; Cell cycle |
| Core Tip |
Colon cancer is one of the most common malignancies worldwide, and chemotherapy is a widely used strategy in colon cancer clinical therapy. However, many patients eventually relapse and develop drug resistance and chemotherapy resistance. This is one of the main causes of chemotherapeutic failure. Tetramethylpyrazine (TMP) has been proven to exhibit a beneficial effect in many types of malignant tumors. Here, we find out that TMP can induce apoptosis and inhibits proliferation of colon cancer cell, suggesting that TMP might serve as a potential novel therapeutic drug in the treatment of human colon cancer. |
| Publish Date |
2021-06-11 09:22 |
| Citation |
Li H, Hou YX, Yang Y, He QQ, Gao TH, Zhao XF, Huo ZB, Chen SB, Liu DX. Tetramethylpyrazine inhibits proliferation of colon cancer cells in vitro. World J Clin Cases 2021; 9(18): 4542-4552 |
| URL |
https://www.wjgnet.com/2307-8960/full/v9/i18/4542.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v9.i18.4542 |
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