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Articles Published Processes
5/7/2021 9:15:56 AM | Browse: 758 | Download: 1752
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Received |
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2020-12-27 16:40 |
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Peer-Review Started |
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2020-12-27 17:00 |
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First Decision by Editorial Office Director |
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2021-02-14 06:38 |
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Return for Revision |
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2021-02-14 06:38 |
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Revised |
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2021-02-24 22:51 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2021-04-06 08:11 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2021-04-14 14:20 |
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Articles in Press |
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2021-04-14 14:20 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2021-04-25 04:00 |
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Publish the Manuscript Online |
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2021-05-07 09:15 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Immunology |
| Manuscript Type |
Review |
| Article Title |
Hypoxia and its impact on the tumour microenvironment of gastroesophageal cancers
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Ross King, Conall Hayes, Claire L Donohoe, Margaret R Dunne, Maria Davern and Noel E Donlon |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Noel E Donlon, BM BCh, Surgical Oncologist, Department of Surgery, St. James’s Hospital Campus, Trinity Translational Medicine Institute, James Street, Dublin D8, Ireland. donlonn@tcd.ie |
| Key Words |
Esophageal cancer; Gastric cancer; Tumor hypoxia; Tumour microenvironment; Gastroesophageal cancer |
| Core Tip |
Improved methods in measuring the oxygen status in the tumour microenvironment have allowed for a better understanding of the role of hypoxia and how it contributes to tumour progression and treatment resistance. These methods include non-invasive imaging techniques as well as validated hypoxic molecular signatures. Specific hypoxia-targeted therapies have not lived up to their expectations but may have potential application in combination with traditional treatment approaches in gastroesophageal cancer. |
| Publish Date |
2021-05-07 09:15 |
| Citation |
King R, Hayes C, Donohoe CL, Dunne MR, Davern M, Donlon NE. Hypoxia and its impact on the tumour microenvironment of gastroesophageal cancers. World J Gastrointest Oncol 2021; 13(5): 312-331 |
| URL |
https://www.wjgnet.com/1948-5204/full/v13/i5/312.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v13.i5.312 |
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