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Articles Published Processes
8/26/2014 5:16:00 PM | Browse: 1211 | Download: 1056
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Received |
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2013-10-09 08:40 |
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Peer-Review Started |
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2013-10-09 22:26 |
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To Make the First Decision |
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2014-01-09 20:16 |
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Return for Revision |
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2014-01-19 20:25 |
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Revised |
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2014-02-10 20:52 |
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Second Decision |
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2014-03-13 13:50 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-03-13 16:47 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2014-05-19 07:57 |
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Publish the Manuscript Online |
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2014-05-28 11:45 |
Category |
Transplantation |
Manuscript Type |
Topic Highlights |
Article Title |
Transfusion and coagulation management in liver transplantation
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Manuscript Source |
Invited Manuscript |
All Author List |
Ben Clevenger and Susan V Mallett |
Funding Agency and Grant Number |
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Corresponding Author |
Susan V Mallett, MBBS, FRCA, Consultant Anaesthetist, Department of Anaesthesia, Royal Free NHS Foundation Trust, Pond Street, London NW3 2QG, United Kingdom. susan.mallett@nhs.net |
Key Words |
Liver disease; Transplantation; Coagulation; Transfusion; Patient blood management; Thromboelastography; Cell salvage |
Core Tip |
Liver transplantation was historically associated with major blood loss. Over the years, improvements in both surgical and anaesthetic management have made transfusion free transplantation an increasingly attainable reality. Research into the complex nature of the coagulopathy of liver disease, has led to the concept that the haemostatic profile is “re-balanced” in these patients, and that stable patients do not have an inherent bleeding diathesis, but rather a reduced reserve, and can be readily tipped towards a bleeding or thrombotic tendency. This review article discusses the various approaches that can be taken to adopt the principles of patient blood management in these patients. |
Publish Date |
2014-05-28 11:45 |
Citation |
Clevenger B, Mallett SV. Transfusion and coagulation management in liver transplantation. World J Gastroenterol 2014; 20(20): 6146-6158 |
URL |
http://www.wjgnet.com/1007-9327/full/v20/i20/6146.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v20.i20.6146 |
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