Publication Name	World Journal of Gastroenterology
Manuscript ID	6214
Country	China

Received	2013-10-09 08:49
Peer-Review Started	2013-10-10 08:43
To Make the First Decision	2014-02-13 16:00
Return for Revision	2014-02-20 14:34
Revised	2014-03-04 22:40
Second Decision	2014-05-14 09:09
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-05-14 09:41
Articles in Press	2014-05-23 11:08
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-05-22 01:24
Typeset the Manuscript	2014-08-16 16:53
Publish the Manuscript Online	2014-08-29 11:57

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Meta-Analysis
Article Title	Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and gastric cancer susceptibility
Manuscript Source	Invited Manuscript
All Author List	Lei-Zhou Xia, Yi Liu, Xiao-Zhou Xu, Peng-Cheng Jiang, Gui Ma, Xue-Feng Bu, Yong-Jun Zhang, Feng Yu, Ke-Sen Xu and Hua Li
Funding Agency and Grant Number
Corresponding Author	Correspondence to: Hua Li, MD, Department of General Surgery, Affiliated People’s Hospital, Jiangsu University, No. 8, Dianli Road, Zhenjiang 212002, Jiangsu Province, China. drlihua212@163.com
Key Words	Methylenetetrahydrofolate reductase; Polymorphism; Gastric cancer; Meta-analysis
Core Tip	Many studies have reported associations of methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms with susceptibility to gastric cancer (GC). There are several relevant published meta-analyses about this subject. Nevertheless, these articles failed to analysis MTHFR polymorphisms and GC risk per se in detail as follows. They failed to investigate the difference between gastric cardia cancer and non-cardia GC, and the distinction between diffuse and intestinal subtypes. Consequently, we performed a meta-analysis to clarify the roles of MTHFR C677T and A1298C polymorphisms in GC susceptibility among the eligible studies.
Publish Date	2014-08-29 11:57
Citation	Xia LZ, Liu Y, Xu XZ, Jiang PC, Ma G, Bu XF, Zhang YJ, Yu F, Xu KS, Li H. Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and gastric cancer susceptibility. World J Gastroenterol 2014; 20(32): 11429-11438
URL	http://www.wjgnet.com/1007-9327/full/v20/i32/11429.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i32.11429

Full Article (PDF)	WJG-20-11429.pdf
Full Article (Word)	WJG-20-11429.doc
Manuscript File	6214-Review.doc
Answering Reviewers	6214-Answering reviewers.pdf
Copyright License Agreement	6214-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	6214-Language certificate.pdf
Peer-review Report	6214-Peer reviews.pdf
Scientific Editor Work List	6214-Scientific editor work list.pdf