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3/17/2021 6:19:34 AM | Browse: 539 | Download: 1131
Publication Name World Journal of Gastroenterology
Manuscript ID 62252
Country/Territory Poland
Received
2021-01-11 18:32
Peer-Review Started
2021-01-11 18:33
To Make the First Decision
Return for Revision
2021-01-23 03:21
Revised
2021-01-24 20:40
Second Decision
2021-02-23 01:22
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-03-01 04:24
Articles in Press
2021-03-01 04:24
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2021-03-08 04:38
Publish the Manuscript Online
2021-03-17 06:19
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Infectious Diseases
Manuscript Type Review
Article Title Genotype 3-hepatitis C virus’ last line of defense
Manuscript Source Invited Manuscript
All Author List Dorota Zarębska-Michaluk
ORCID
Author(s) ORCID Number
Dorota Zarębska-Michaluk http://orcid.org/0000-0003-0938-1084
Funding Agency and Grant Number
Corresponding Author Dorota Zarębska-Michaluk, N/A, Professor, Department of Infectious Diseases, Jan Kochanowski University, Żeromskiego 5, Kielce 25-369, Świętokrzyskie, Poland. dorota1010@tlen.pl
Key Words Hepatitis C virus; Genotype 3; Antiviral treatment; Interferon; Direct-acting antivirals; Pangenotypic
Core Tip Genotype 3 which is second in frequency worldwide, is unique among genotypes of hepatitis C virus in its higher rate of steatosis, accelerated fibrosis progression, and lower cure rates. This paper describes the genotype-specific mechanisms of liver injury and provides an overview of therapeutic options. Currently, available highly potent pangenotypic regimens have revolutionized the treatment of genotype 3 infection, however, patients with liver cirrhosis and those who fail to response to direct-acting antiviral therapy still present a therapeutic challenge.
Publish Date 2021-03-17 06:19
Citation Zarębska-Michaluk D. Genotype 3-hepatitis C virus’ last line of defense. World J Gastroenterol 2021; 27(11): 1006-1021
URL https://www.wjgnet.com/1007-9327/full/v27/i11/1006.htm
DOI https://dx.doi.org/10.3748/wjg.v27.i11.1006
Full Article (PDF) WJG-27-1006.pdf
Full Article (Word) WJG-27-1006.docx
Manuscript File 62252_Auto_Edited_LM.docx
Answering Reviewers 62252-Answering reviewers.pdf
Audio Core Tip 62252-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 62252-Conflict-of-interest statement.pdf
Copyright License Agreement 62252-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 62252-Language certificate.pdf
Peer-review Report 62252-Peer-review(s).pdf
Scientific Misconduct Check 62252-Scientific misconduct check.pdf
Scientific Editor Work List 62252-Scientific editor work list.pdf